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Does Microglial Activation Promote Lesion Growth and Progression Among Multiple Sclerosis Patients

Enrolling By InvitationN/A

Sponsor: Turku University Hospital

Conditions: Multiple Sclerosis

Countries: Finland

The purpose of this study is to assess whether increased microglial activation (measured using TSPO-PET) at lesion rim is associated with more rapid lesion growth during 10 year follow up.

Eligibility overview

Sex: ALL

Age: 30 Years to 80 Years

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Participation to a previous PET imaging study of Airas group
* MS diagnosis

Exclusion Criteria:

* Patients with other neurodegenerative disease than MS
* Contraindication to MR scan investigations
* Patients with claustrophobia, or a history of moderate to severe anxiety disorder or panic attacks (which could potentially lead to preterm termination of the imaging)

Locations (1)

Turku, Southwest Finland, Finland