NCT lookup

Pull any trial record directly from ClinicalTrials.gov.

Blinded Dry Mouth Spray Crossover Study

CompletedNA

Sponsor: Jonas Johnson

Conditions: Xerostomia, Head and Neck Cancer, Xerostomia Following Radiotherapy

Interventions: Remineralizing Extreme Dry Mouth Spray with Xylitol, Alcohol-Free Moisturizing Dry Mouth Spray

Countries: United States

To identify the effectiveness of two mouth sprays at relieving symptoms of xerostomia in patients who have received radiation for carcinoma of the head and neck. To assess patient quality of life and mouth acidity following use of two mouth sprays meant to relieve symptoms of xerostomia in patients who have received radiation for carcinoma of the head and neck.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* biopsy-proven oral cavity, oropharynx, larynx, and hypopharynx carcinoma
* who received primary radiation with curative intent (\>50 Gray in 20 fractions)
* radiation treatment completed greater than 6 months ago
* who endorse xerostomia

Exclusion Criteria:

* evidence of metastasis or recurrent disease
* Current use of pilocarpine, antidepressants, anticholinergic drugs, or any other medication that has an effect on salivation
* those who have documented medical conditions associated with xerostomia such as Sjogren's Syndrome
* those who use oral inhalants for the treatment of respiratory disease

Locations (2)

Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States