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Aquaporin-4 Single Nucleotide Polymorphisms in Patients With Idiopathic and Familial Parkinson's Disease

CompletedN/A

Sponsor: University of Exeter

Conditions: Parkinson Disease

Interventions: Study procedure

Countries: United Kingdom

The purpose of this study is to understand the relationship between problems in sleep, genetic variations in the Aquaporin-4 gene (AQP4), and the development of Parkinson's Disease.

Eligibility overview

Sex: ALL

Age: 18 Years to 85 Years

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* 18-85 years of age
* Able to give informed consent
* Able to perform online neuropsychological examinations
* Diagnosis of PD according to Brain Bank Criteria
* No presence or personal or family history of other neurological or psychiatric disorders

Exclusion Criteria:

* Presence of other neurological disorders and known intracranial co-morbidities such as stroke, haemorrhage, space-occupying lesions
* Inability to perform online neuropsychological assessment
* Inability to have access to informatics technology to perform the online assessment tests
* Inability to travel for the assessments
* Native language different from English

Locations (4)

Ashford, United Kingdom
Exeter, United Kingdom
Llanelli, United Kingdom
London, United Kingdom