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Sponsor: University of Colorado, Denver
Conditions: Multiple Sclerosis
Interventions: Proximal Resistance Training
Countries: United States
The objective of this study is to pilot a 10-week resistance and functional movement intervention targeting proximal muscles in 40 people with MS. The investigators will assess implementation feasibility (recruitment, fidelity, retention, satisfaction), collect pilot data for key walking function outcomes, and examine movement-pattern and activity behavior mechanisms. Walking function will be measured by walking capacity (6-Minute Walk Test - 6MWT) and PA quantity (average steps/ day over 10 days). Movement-pattern mechanisms will be measured using 3D motion capture analysis (pelvis and trunk kinematics). Activity behavior mechanisms will be measured by patient-reported outcome questionnaires (perception of walking ability, self-efficacy, and readiness to change).
Sex: ALL
Age: 18 Years to 64 Years
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria. * 18-64 years old * Neurologist-confirmed diagnosis of MS * Able to walk at least 100 meters without an assistive device * Expanded Disability Status Scale - EDSS \< 6 * Have their own tablet/phone/computer capable of video calls/Zoom meetings. Exclusion Criteria. * Other conditions limiting their ability to exercise or walk * Unsafe to exercise as determined by a neurologist or physical therapist * Currently undergoing physical therapy * Unable to provide consent or follow simple directions * Have an MS-related exacerbation or changes to their disease-modifying drug therapy in the month prior to enrollment * A 25 foot walk test time of \> 4.5 seconds
- Aurora, Colorado, United States