NCT lookup
Pull any trial record directly from ClinicalTrials.gov.
Sponsor: Washington University School of Medicine
Conditions: HIV/AIDS
Interventions: SOC-REC/SOC-OIC, SOC-REC/CCT, SOC-REC/IP-NAV, E-NAV/SOC-OIC, E-NAV/CCT
Countries: Kenya
Adolescents and young adults (AYA) with HIV face unique challenges to engagement in care and their ability to achieve optimal health outcomes. The investigators hypothesize that developmentally-tailored behavioral interventions will improve engagement in HIV care and viral suppression (per current MOH guidelines) among AYA with HIV in Kenya. This two stage study will initially randomize 880 AYA with HIV to either standard of care (SOC) or electronic navigation to prevent treatment lapse. Participants who have a lapse will be re-randomized to SOC, in-person peer navigation, or conditional cash transfers. Formative work will be conducted initially to tailor the interventions to AYA and then later to assess AYA perception, experience, and satisfaction with the interventions. We will evaluate the most effective and cost-effective intervention and sequence of interventions to inform HIV program managers, public policy makers, and other key stakeholders the best approaches to improve engagement of care of AYA with HIV.
Sex: ALL
Age: 14 Years to 24 Years
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria: * HIV-infection, on or initiating ART, * 14-24 years of age, * Living \> 6 months in Kisumu County, Kenya in previous year, * Capable of informed consent (\> 18 years) or with a legal caregiver available for consent (14-\<18 years), * Access to a cell phone, * Ability to read or be read short message service (SMS) messages, * Willingness to be contacted by clinic upon missed appointment, * For AYA who report phone sharing must have disclosed to the person sharing the phone. * Additionally, we will include AYA who are aware of their HIV status or whose caregivers agree to assisted disclosure. Exclusion Criteria: * AYA who participated in ADAPT-R, * Those planning to move out of Kisumu County, those acutely ill and requiring hospitalization, * Those who report sharing phones but have not disclosed to the person sharing the phone
- Kisumu, Kenya