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Evaluation of a New Predictive Test of Preterm Birth in Case of Threatened Preterm Labor
Evaluation of a New Predictive Test of Preterm Birth in Case of Threatened Preterm Labor

NCT04374916

RecruitingNA

Sponsor: University Hospital, Strasbourg, France

Conditions: Threatened Preterm Labor, Preterm Delivery

Interventions: Premaquick®, PARTOSURE®

Countries: France

Threatened preterm labor (TPL) is defined by cervical changes and regular and painful uterine contractions occurring between 24 and 36 + 6 weeks of gestation that may or may not lead to premature labor and delivery. There is no reliable way to predict preterm delivery. The study's hypothesis is that the Premaquick® test can improve the prediction of preterm delivery. The investigators also want to compare this test with the Partosure® (Placental alpha microglobulin-1) test.

Eligibility overview

Sex: FEMALE

Age: 18 Years to

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Patient aged \> 18 years (with no upper age limit)
* Patient affiliated to a social security health regime
* Between 24 and 33 + 6 weeks of gestation (amenorrhea)
* Singleton pregnancy
* Patient with a TPL: Uterine contractions during the last 24 hours felt by the patient, painful or not, and cervix less than or equal to 25 mm on endovaginal ultrasound
* Having signed an informed consent form

Exclusion Criteria:

* Twin pregnancy
* Sexual intercourse less than 24 hours from inclusion
* Cervical cerclage
* Abundant metrorrhagia
* Premature rupture of membranes
* Pre-eclampsia
* Congenital malformation
* Presence of a placenta previa
* Pelvic examination in the previous 24 hours (compared to inclusion)
* Patient under guardianship, curatorship or safeguard of justice
* Persons deprived of their liberty by judicial or administrative decision
* Persons under psychiatric care under duress
Locations (1)
  • Strasbourg, France