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Tromsø Birch Rust Allergy Study. Allergy to Birch Rust, a Possible Explanation to Seasonal Airway Allergy During Autumn?

NCT04322838

CompletedN/A

Sponsor: University Hospital of North Norway

Conditions: Hypersensitivity, Immediate, Allergy

Interventions: MeDALL questionnaire for allergic diseases, Registration of allergic symptoms, Skin Prick Test, Specific IgE in serum, Nasal provocation test

Countries: Norway

In this project we study if spores from birch rust fungi (Melampsoridium Betulinum = MB) may be the eliciting allergen in patients with seasonal airway allergy during autumn in North Norway. Patients with suspected allergy to MB are compared with non-allergic controls using data about allergic disease and daily allergic symptoms during autumn. Daily spread of MB spores are compared with daily variations in allergic symptoms. Sensitization to MB and MB allergy are tested with skin prick test, specific immunoglobulin E (IgE) in serum, nasal provocation test and basophil activation test (BAT).

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Self reported seasonal airway allergic symptoms during autumn

Exclusion Criteria:

* Perennial airway allergic symptoms without worsening during autumn

Locations (1)

Tromsø, Norway