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NO Prevention of COVID-19 for Healthcare Providers

TerminatedPhase 2

Sponsor: Massachusetts General Hospital

Conditions: Coronavirus Infections, Healthcare Associated Infection

Interventions: Inhaled nitric oxide gas

Countries: United States

Thousands of healthcare workers have been infected with SARS-CoV-2 and contracted COVID-19 despite their best efforts to prevent contamination. No proven vaccine is available to protect healthcare workers against SARS-CoV-2. This study will enroll 470 healthcare professionals dedicated to care for patients with proven SARS-CoV-2 infection. Subjects will be randomized either in the observational (control) group or in the inhaled nitric oxide group. All personnel will observe measures on strict precaution in accordance with WHO and the CDC regulations.

Eligibility overview

Sex: ALL

Age: 18 Years to 99 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

1. Age ≥18 years
2. Scheduled to work with SARS-CoV-2 infected patients for at least 3 days in a week.

Exclusion Criteria:

1. Previous documented SARS-CoV-2 infections and subsequent negative SARS-CoV-2 rt-PCR test.
2. Pregnancy
3. Known hemoglobinopathies.
4. Known anemia

Locations (1)

Boston, Massachusetts, United States