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A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa
A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa

NCT04092452

CompletedPhase 2

Sponsor: Pfizer

Conditions: Acne Inversa

Interventions: PF-06650833, PF-06700841, PF-06826647, Placebo

Countries: United States, Australia, Canada

This is a study with 3 kinase inhibitors (PF 06650833, PF 06700841 and PF 06826647) in participants with moderate to severe HS. The study will have a maximum duration of approximately 26 weeks. This includes an up to 6-week Screening Period, a 16 week Dosing Period and a 4 week Follow up Period.

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* male or female participants, between 18-75, with a diagnosis of moderate to severe Hidradenitis Suppurativa

Exclusion Criteria:

* History of human immunodeficiency virus (HIV) or positive HIV serology at screening,
* Infected with hepatitis B or hepatitis C viruses.
* Have evidence of active or latent or inadequately treated infection with Mycobacterium tuberculosis (TB)
Locations (77)
  • Birmingham, Alabama, United States
  • Birmingham, Alabama, United States
  • Birmingham, Alabama, United States
  • Birmingham, Alabama, United States
  • Scottsdale, Arizona, United States
  • Fremont, California, United States
  • Long Beach, California, United States
  • Los Angeles, California, United States
  • San Francisco, California, United States
  • San Francisco, California, United States
  • San Francisco, California, United States
  • Santa Monica, California, United States
  • Bridgeport, Connecticut, United States
  • Shelton, Connecticut, United States
  • Jacksonville, Florida, United States
  • Jacksonville, Florida, United States
  • Largo, Florida, United States
  • Miami, Florida, United States
  • North Miami Beach, Florida, United States
  • Ocala, Florida, United States
  • Ocala, Florida, United States
  • Ocala, Florida, United States
  • Orange Park, Florida, United States
  • Ormond Beach, Florida, United States
  • Pembroke Pines, Florida, United States
  • Tampa, Florida, United States
  • Tampa, Florida, United States
  • Newnan, Georgia, United States
  • Sandy Springs, Georgia, United States
  • Watkinsville, Georgia, United States
  • + 47 more on CT.gov