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RIPC on Activity, Fatigue and Gait in MS

CompletedNA

Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust

Conditions: Multiple Sclerosis

Interventions: Ischaemic Preconditioning, Sham

Countries: United Kingdom

This study evaluates whether Remote Ischaemic Preconditioning (RIPC) can improve activity, gait and fatigue in people with Multiple Sclerosis. Half the participants will receive RIPC, the other half will receive a sham treatment.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Diagnosis of MS as per the McDonald's criteria
* Sufficient cognitive ability and understanding of the English language to give informed consent and complete study questionnaires
* Ability to walk for 6 minutes without rest
* Resting Systolic BP of more than 100mmHg
* Resting Systolic BP of less than 170mmHg

Exclusion Criteria:

* Cognitive difficulties or insufficient English to allow understanding of consent and study questionnaires
* Inability to walk
* Other systemic illness affecting exercise tolerance
* Resting Systolic BP of less than 100mmHg
* Resting systolic BP of 170mmHg or more

Locations (1)

Sheffield, South Yorkshire, United Kingdom