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Dose Ranging Study To Assess Efficacy, Safety and Tolerability Of PF-06700841 Topical Cream In Psoriasis
Dose Ranging Study To Assess Efficacy, Safety and Tolerability Of PF-06700841 Topical Cream In Psoriasis

NCT03850483

CompletedPhase 2

Sponsor: Pfizer

Conditions: Psoriasis

Interventions: PF-06700841, Vehicle (Placebo)

Countries: United States, Australia, Bulgaria, Canada, Denmark, Germany, Hungary, Japan

This is a Phase 2b, randomized, double blind, vehicle controlled, parallel group, multicenter study in participants with mild to moderate plaque psoriasis. The duration of study participation will be approximately 22 weeks, including up to a 6 week screening period, 12 week treatment period, and approximately 4 week follow up period. Approximately 280 participants are planned to be randomized into the study.

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* plaque psoriasis for 6 months
* PGA score mild or moderate
* body surface area (BSA) 2-15%

Exclusion Criteria:

* other skin conditions that would interfere with the evaluation of psoriasis
* history of herpes zoster or simplex
* Infected with Mycobacterium tuberculosis
Locations (79)
  • Scottsdale, Arizona, United States
  • Scottsdale, Arizona, United States
  • Hot Springs, Arkansas, United States
  • Anaheim, California, United States
  • Anaheim, California, United States
  • Encinitas, California, United States
  • Fountain Valley, California, United States
  • Santa Monica, California, United States
  • Bridgeport, Connecticut, United States
  • Shelton, Connecticut, United States
  • Clearwater, Florida, United States
  • DeLand, Florida, United States
  • Jacksonville, Florida, United States
  • Ocala, Florida, United States
  • Ocala, Florida, United States
  • Ocala, Florida, United States
  • Orange Park, Florida, United States
  • Tampa, Florida, United States
  • West Dundee, Illinois, United States
  • Clarksville, Indiana, United States
  • Louisville, Kentucky, United States
  • Baton Rouge, Louisiana, United States
  • Saint Joseph, Missouri, United States
  • Berlin, New Jersey, United States
  • East Windsor, New Jersey, United States
  • Bayside, New York, United States
  • High Point, North Carolina, United States
  • Raleigh, North Carolina, United States
  • Tulsa, Oklahoma, United States
  • Rapid City, South Dakota, United States
  • + 49 more on CT.gov