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Inclusion criteria:

* Males or females between the ages of 18 and 65 suffering from seasonal allergic rhinitis provoked by ragweed pollen.
* Having a 2-year history of seasonal allergic rhinitis with positive skin prick test to ragweed allergen at screening with a wheal diameter at least 3 mm larger than that produced by the negative control.
* Subjects with antecedents of allergic seasonal allergic rhinitis symptom aggravation when exposed to pollen and air pollutants (i.e., cleaning products, diesel, paints).
* Subjects having a total nasal symptom score ≥3 in Period 1 (Visit 2).

Exclusion criteria:

* History of anaphylaxis to ragweed pollen.
* History of asthma. Mild asthmatics treated only with pro re nata short-acting beta2-agonists, 2 doses or less per week can be enrolled.
* History of chronic sinusitis.
* History of systemic disease affecting the immune system.
* Evidence of any active or suspected bacterial, viral, fungal or parasitic infections within 30 days prior to allergen challenge.
* Any history of Grade 4 anaphylaxis due to any cause as defined by the Common Terminology Criteria for Adverse Event grading criteria ("Life threatening consequences: urgent intervention indicated").
* Presence or history of drug hypersensitivity to fexofenadine.
* Subjects receiving build-up injections of pollen allergen immunotherapy (those on stable maintenance dosing can be included).
* Subjects taking any forbidden treatments/nutriments.

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

• Canada, Canada