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The Effectiveness Of Atezolizumab In Patients With Locally-Advanced Or Metastatic Non-Small Cell Lung Cancer After Prior Chemotherapy

NCT03559647

CompletedN/A

Sponsor: Hoffmann-La Roche

Conditions: Non-Small Cell Lung Cancer (NSCLC)

Interventions: Atezolizumab

Countries: Germany

Hyperion Is A Prospective, Multicenter, Non-Interventional, Two-Cohort Study Collecting Primary Data In Patients With Locally Advanced Or Metastatic NSCLC Of Squamous Or Non-Squamous Histology After Prior Chemotherapy Being Treated With Atezolizumab In Routine Clinical Practice.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Diagnosis of locally advanced or metastatic NSCLC (histologically or cytologically confirmed stage IIIB/stage IV) and prior chemotherapy
* Decision to be treated with Atezolizumab according to Summary of Product Characteristics (SmPC) by treating physician, independent of this non-interventional study
* No contraindication to treatment with Atezolizumab

Retrospective Inclusion:

* Participants may be included retrospectively. Retrospective inclusion and documentation is limited to up to 9 weeks after initial start of therapy with Atezolizumab (corresponding to a maximum of 3 treatment cycles with drug administrations at 3-week intervals), corresponding to a maximum of 9 weeks prior to date of informed consent. Quality of life for this population will be captured and assessed retrospectively with a modified questionnaire for the period immediately prior to treatment start until study inclusion. participants who started Atezolizumab therapy more than 9 weeks prior to ICF being obtained may not be included in the study.
* Participants who give consent to be retrospectively enrolled but have already discontinued Atezolizumab for reasons such as loss of clinical benefit or toxicity may also take part in the study, given their first administration of Atezolizumab is within 9 weeks of consenting to take part, and they meet all other eligibility criteria.

Exclusion Criteria:

Patients not eligible for Atezolizumab treatment according to SmPC

Locations (94)

Aschaffenburg, Germany
Aschaffenburg, Germany
Augsburg, Germany
Bad Reichenhall, Germany
Baden-Baden, Germany
Bamberg, Germany
Berlin, Germany
Berlin, Germany
Berlin, Germany
Berlin, Germany
Bielefeld, Germany
Bielefeld, Germany
Bochum, Germany
Cologne, Germany
Coswig, Germany
Donauwörth, Germany
Dortmund, Germany
Dresden, Germany
Duisburg, Germany
Eberswalde, Germany
Euskirchen, Germany
Frankenthal/Pfalz, Germany
Frankfurt, Germany
Frankfurt am Main, Germany
Frankfurt am Main, Germany
Fürth, Germany
Garbsen, Germany
Georgsmarienhütte, Germany
Gera, Germany
Greifenstein, Germany
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