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Video Games Therapy on Balance and Cognitive Functions in Mild to Moderate Impaired Multiple Sclerosis Patients.

CompletedNA

Sponsor: University Hospital of Ferrara

Conditions: Multiple Sclerosis

Interventions: Video game therapy, Balance platform therapy

Countries: Italy

Multiple Sclerosis (MS) is often characterized by the presence of balance and cognitive impairments. Cognitive functions play a key role in balance control. Simultaneously performing cognitive tasks decreases walking and balance ability (Dual-Task cost). Rehabilitative treatment of patients with MS does not have to consider separately the motor and cognitive aspects. Video-Game Therapy (VGT) is a novel tool that allows a multimodal training approach. VGT typically provides augmented feedback during training that can contribute to learning motor skills. The main objective of this exploratory study will be to test the effects of a commercially available VGT on balance and cognitive function in ambulatory MS patients compared to a standardized balance platform training (BPT). Secondary, we will explore the effects of VGT and BPT on other domains that are usually impaired in MS population and that can be improved by motor rehabilitation, such as psychological well-being, fatigue and Quality of Life.

Eligibility overview

Sex: ALL

Age: 18 Years to 60 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* diagnosis of MS (primary or secondary progressive, relapsing-remitting), without relapses in the preceding 3 months
* mild to moderate balance impairments with increased fall risk, defined as TUG \> 8.4s
* disability rate definited by Kurtzke Expanded Disability Status Scale (EDSS) score from 4 to 5.5,

Exclusion Criteria:

* other conditions that may affect motor function
* impaired cognitive functioning (Mini Mental Status Examination score less than 24)
* visual impairments (daltonism and visual acuity deficit)
* medical conditions that might interfere with the ability to complete the study protocol safely.

A group of healthy subjects matched for age and sex will be involved for a comparison on the instrumental data (force platforms).

Locations (2)

Ferrara, Emilia-Romagna, Italy
Ferrara, Italy