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Study to Compare Oral PF-06651600, PF-06700841 and Placebo in Subjects With Moderate to Severe Ulcerative Colitis
Study to Compare Oral PF-06651600, PF-06700841 and Placebo in Subjects With Moderate to Severe Ulcerative Colitis

NCT02958865

CompletedPhase 2

Sponsor: Pfizer

Conditions: Ulcerative Colitis

Interventions: PF-06651600 or Placebo, PF-06700841 or Placebo, PF-06700841, PF-06651600

Countries: United States, Austria, Bulgaria, Czechia, Denmark, Georgia, Germany, Hungary

The purpose of this study is to determine whether PF-06651600 and PF-06700841 are effective in treatment of moderate to severe ulcerative colitis.

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Diagnosis of ulcerative colitis for greater than/equal to 3 months.
* Moderate to severe active ulcerative colitis
* Inadequate response to, loss of response to, or intolerance to at least one conventional therapy for UC.

Exclusion Criteria:

* Pregnant or breastfeeding
* Clinical findings suggestive of Crohn's Disease
* History of bowel surgery within 6 months
Locations (189)
  • Dothan, Alabama, United States
  • Dothan, Alabama, United States
  • Long Beach, California, United States
  • Los Angeles, California, United States
  • San Diego, California, United States
  • San Diego, California, United States
  • San Diego, California, United States
  • Colorado Springs, Colorado, United States
  • Colorado Springs, Colorado, United States
  • Bristol, Connecticut, United States
  • Bristol, Connecticut, United States
  • Plainville, Connecticut, United States
  • Clearwater, Florida, United States
  • Miami, Florida, United States
  • Miami, Florida, United States
  • Orlando, Florida, United States
  • Orlando, Florida, United States
  • Orlando, Florida, United States
  • Oak Lawn, Illinois, United States
  • Chevy Chase, Maryland, United States
  • Chevy Chase, Maryland, United States
  • Chevy Chase, Maryland, United States
  • Columbia, Maryland, United States
  • Columbia, Maryland, United States
  • Boston, Massachusetts, United States
  • Chestnut Hill, Massachusetts, United States
  • New York, New York, United States
  • New York, New York, United States
  • New York, New York, United States
  • New York, New York, United States
  • + 159 more on CT.gov