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Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: Case-control
Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: Case-control

NCT02890147

CompletedN/A

Sponsor: Fundación Pública Andaluza Progreso y Salud

Conditions: Healthy Subjects

Countries: Austria, Belgium, France, Germany, Hungary, Italy, Portugal, Spain

Connective tissue diseases (CTD) or systemic autoimmune diseases (SADs) as they are known today are a group of chronic inflammatory conditions with autoimmune aetiology with few treatment options and difficult diagnosis.Brest team contribute to perform a new classification of the following systemic autoimmune diseases in a European Union's Seventh Framework Programme. The aim of this research is to constitute a Healthy Volunteers cohort to compare with systemic autoimmune diseases cohort into molecular clusters instead of clinical entities through the determination of molecular profiles using several "Omics" techniques.

Eligibility overview

Sex: ALL

Age: 18 Years to

Healthy volunteers: Yes

Study type: OBSERVATIONAL

Eligibility criteria
Inclusion Criteria:

* Aged 18 years or older at the time of consent
* Signed the informed consent form

Exclusion Criteria:

* Individuals on chronic medication.
* Individuals suffering from any inflammatory, autoimmune, allergic or infectious condition and if possible without a history of autoimmune disease, particularly thyroid disease or other diseases that may modify cellular profiles in blood.
* Pregnant women.
Locations (17)
  • Vienna, Austria
  • Leuven, Belgium
  • Brest, France
  • Berlin, Germany
  • Hanover, Germany
  • Szeged, Hungary
  • Milan, Italy
  • Milan, Italy
  • Porto, Portugal
  • Barcelona, Spain
  • Córdoba, Spain
  • Granada, Spain
  • Granada, Spain
  • Granada, Spain
  • Málaga, Spain
  • Santander, Spain
  • Geneva, Switzerland