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Patient and Provider Assessment of Lipid Management Registry

CompletedN/A

Sponsor: Duke University

Conditions: Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes, Chronic Kidney Disease (CKD)

Countries: United States

The purpose of the Patient and Provider Assessment of Lipid Management Registry (PALM) is to gain a better understanding of physicians' cholesterol medication prescribing practices, patient and physician attitudes and beliefs related to cholesterol management, and current utilization of cholesterol-lowering therapies given the new ACC/AHA guideline recommendations. The PALM Registry hopes to allow for the design of ways to improve cholesterol management and decrease the burden of cardiovascular disease (CVD) in the US.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

1. Prior evidence of clinical atherosclerotic cardiovascular disease (ASCVD) which can include any of the following:

   * Hospitalization for acute myocardial infarction or unstable angina
   * Coronary revascularization or chronic coronary artery disease with or without angina
   * Other arterial (carotid, abdominal, renal or lower extremity) revascularization (e.g., surgical bypass, percutaneous intervention, arterial vascular reconstruction, abdominal aortic aneurysm repair, excluding dialysis fistulas or arteriovenous grafts).
   * Ischemic stroke or transient ischemic attack (TIA)
   * Imaging evidence of \> 70% diameter stenosis in any carotid artery or clinical documentation of severe carotid stenosis
   * Peripheral arterial disease secondary to atherosclerosis (e.g., aortic aneurysm, ankle brachial index \<0.9, imaging evidence of \>50% diameter stenosis in any peripheral artery, or claudication)
2. Currently on statin therapy
3. Low density lipoprotein cholesterol (LDL-C) level ≥ 130 mg/dL within the last 2 years (treated or untreated)
4. Age ≥ 65 years
5. Age ≥ 40 years with at least 1 of the following:

   * Diabetes
   * Chronic Kidney Disease (CKD), defined as eGFR \<60 ml/min or documented stage III or higher CKD
   * 10-year ASCVD risk ≥ 5% (per the 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk)
   * 2 or more of the following characteristics: Male sex; Systolic BP \> 140 mmHg or on medication for hypertension; Current tobacco use

Exclusion Criteria:

1. Unable or unwilling to provide informed consent, including but not limited to cognitive or language barriers (reading or comprehension)
2. Anticipated life expectancy less than 6 months
3. Participation in any clinical trial involving a medical treatment at the time of enrollment

Locations (14)

Little Rock, Arkansas, United States
San Pedro, California, United States
Ventura, California, United States
Hialeah, Florida, United States
Hialeah Gardens, Florida, United States
Plantation, Florida, United States
Overland Park, Kansas, United States
Elizabethtown, Kentucky, United States
Saint Paul, Minnesota, United States
Mineola, New York, United States
New York, New York, United States
New Bern, North Carolina, United States
Lansdale, Pennsylvania, United States
Charleston, West Virginia, United States