NCT lookup

Inclusion Criteria:

* Patient 18-75 years of age, inclusive.
* Patient qualifies for primary total knee arthroplasty based on physical exam and medical history, including diagnosis of severe knee pain and disability due to at least one of the following:

  * rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis;
  * collagen disorders and/or avascular necrosis of the femoral condyle;
  * post-traumatic loss of joint configuration, particularly when there is patellofemoral erosion, dysfunction or prior patellectomy;
  * moderate valgus, varus, or flexion deformities;
  * the salvage of previously failed surgical attempts that did not include partial or total knee arthroplasty of the ipsilateral knee.
* Patient is willing and able to complete scheduled study procedures and follow-up evaluations.
* Independent of study participation, patient is a candidate for commercially available Zimmer Persona knee implants implanted in accordance with product labeling.

Exclusion Criteria:

* Patient is currently participating in any other surgical intervention studies or pain management studies.
* Previous history of infection in the affected joint and/or other local/systemic infection that may affect the prosthetic joint.
* Insufficient bone stock on femoral or tibial surfaces.
* Skeletal immaturity.
* Neuropathic arthropathy.
* Osteoporosis or any loss of musculature or neuromuscular disease that compromises the affected limb.
* Stable, painless arthrodesis in a satisfactory functional position.
* Severe instability secondary to the absence of collateral ligament integrity.
* Rheumatoid arthritis accompanied by an ulcer of the skin or a history of recurrent breakdown of the skin.
* Patient has a known or suspected sensitivity or allergy to one or more of the implant materials.
* Patient is pregnant or considered a member of a protected population (e.g., prisoner, mentally incompetent, etc.).
* Patient has previously received partial or total knee arthroplasty for the ipsilateral knee.

• Vienna, Austria
• Clermont-Ferrand, France
• Montpellier, France
• Braunschweig, Germany
• Heidelberg, Germany
• Delft, Netherlands
• Sabadell, Spain
• Zaragoza, Spain
• Leeds, Leeds/UK, United Kingdom
• Clydebank, United Kingdom
• Harrogate, United Kingdom
• Newcastle, United Kingdom