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Sponsor: University Hospital, Bordeaux
Conditions: Dementia, Alzheimer Disease
Interventions: Neuroimaging
Countries: France
It is now acknowledged that Alzheimer's disease is characterized by a long period of pathophysiological change. Developing new strategies to achieve diagnoses as early as possible has become a major goal for therapies aimed at slowing the progression of this disease. While diagnoses currently rely principally on clinical neuropsychology, the typical diagnostic criteria of NINCDS-ADRDA are inapplicable in the early stage of the disease. The goal of our project is to identify very early imaging markers for Alzheimer's disease among patients with no report of cognitive difficulties. In order to achieve this goal, we propose a longitudinal study in an elderly population cohort.
Sex: ALL
Age: 65 Years to —
Healthy volunteers: No
Study type: INTERVENTIONAL
Inclusion Criteria: * At least 65 years old * Be retired from agricultural profession * live in rural area in Gironde (France) Exclusion Criteria: * Lefthanded * having a dementia (MMSE \< 13) * Having a vascular cerebral accident * Parkinson disease * RMI exclusion criteria * \[18F\]-FDG PET SCAN exclusion criteria * Poor health condition does not allowing transport to neuroimaging service
- Bordeaux, France