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Asthma Inflammation Research
Asthma Inflammation Research

NCT01536522

Enrolling By InvitationEARLY_Phase 1

Sponsor: The Cleveland Clinic

Conditions: Asthma, Allergic Asthma, Non-allergic Asthma

Interventions: Nutritional approach for asthma, Low Caloric Shake, whole lung allergen challenge

Countries: United States

The overall goal of the Asthma Inflammation Research \[AIR\] Translational Program is to create an integrated multidisciplinary team for the focused purpose of development of diagnostic and prognostic tests informative for airway inflammation, and for the design of innovative, targeted biologic therapeutics. The overarching aims of the AIR program are to conceptualize, develop, and test the next-generation therapeutics, and novel asthma diagnostic and prognostic tools that will allow us to improve the standard of asthma care.

Eligibility overview

Sex: ALL

Age: 18 Years to 75 Years

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Asthma diagnosed by a medical specialist and/or history of positive methacholine rest and/or reversibility of \>10% of FEV1
* FEV1 is within acceptable limits
* Informed Consent is present

Exclusion Criteria:

* Diabetes (fasting blood sugar \>110 mg/dL)
* Any milk allergies
* Coconut allergies
* BMI \>40 kg/m2,
* Inability to maintain diet intervention
* Current smoking or smoking history of greater than 10 pack-years
* Any other significant respiratory or cardiac disease or the presence of clinically important comorbidities, including, uncontrolled coronary artery disease, acute or and chronic renal failure
Locations (1)
  • Cleveland, Ohio, United States