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An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer (ACORN)

CompletedN/A

Sponsor: Hoffmann-La Roche

Conditions: Colorectal Cancer

Interventions: Bevacizumab, Capecitabine/Oxaliplatin, Fluorouracil/Folinic Acid/Oxaliplatin, Capecitabine, Fluorouracil/Folinic Acid/Irinotecan

Countries: United Kingdom

This prospective, multi-center, observational study will assess the safety and efficacy of Avastin (bevacizumab) in daily practice in patients with metastatic colorectal cancer who have received no previous treatment for advanced disease and are receiving Avastin in combination with a standard of care first-line chemotherapy regimen. Data will be collected for 1.5 years or until death.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: OBSERVATIONAL

Eligibility criteria

Inclusion Criteria:

* Metastatic colorectal cancer with no previous systemic treatment for advanced disease
* Receiving Avastin in combination with a first-line standard of care chemotherapy regimen
* Avastin initiated at the same time as first-line chemotherapy regimen

Exclusion Criteria:

* Investigational, non-standard of care first-line chemotherapy regimen for treatment of metastatic colorectal cancer
* Contraindication to Avastin

Locations (43)

Bath, United Kingdom
Berkshire, United Kingdom
Birmingham, United Kingdom
Birmingham, United Kingdom
Bishop Auckland, United Kingdom
Blackpool, United Kingdom
Bradford, United Kingdom
Bristol, United Kingdom
Bury St Edmunds, United Kingdom
Canterbury, United Kingdom
Carlisle, United Kingdom
Chelsmford, United Kingdom
Cleveland, United Kingdom
Cottingham, United Kingdom
Darlington, United Kingdom
Dudley, United Kingdom
Durham, United Kingdom
Harrogate, United Kingdom
Harrow, United Kingdom
Ipswich, United Kingdom
Kidderminster, United Kingdom
London, United Kingdom
London, United Kingdom
London, United Kingdom
Macclesfield, United Kingdom
Maidstone, United Kingdom
Middlesbrough, United Kingdom
Newcastle upon Tyne, United Kingdom
North Shields, United Kingdom
Northwood, United Kingdom
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