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Is a Diet Necessary When Corticosteroid Treatment is Prescribed?

NCT01420133

CompletedNA

Sponsor: Assistance Publique - Hôpitaux de Paris

Conditions: Autoimmune Diseases, Asthma

Interventions: Regimen, Standard regimen

Countries: France

Few recommendations concerning the diet and dosage to be administered to patients treated with corticosteroids are established. It therefore seems important to study prospectively the indication of a diet low in salt and sugar in patients undergoing corticosteroid therapy, to record side effects observed and to measure their frequency.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion criteria :

* Age \> 18 years
* All patients for whom corticoids initially prescribed at a dose \> 20 mg per 24 hours, during a period of 3 months minimum
* Corticotherapy should be prescribed per os and continuously. (Alternating doses of corticoids, sequential intramuscular or intravenous injection of corticoids are not allowed in this clinical trial)
* All diseases requiring corticotherapy may be subject to this clinical trial. The main pathologies will be systemic autoimmune diseases, asthma or chronic skin diseases justifying prolonged oral corticotherapy.
* Time between first corticoids delivery and randomization \< 1 month
* Patient who gave his non-opposition

Note: Depending on their health condition, patient may receive one or more intravenous injections of methylprednisolone (until 3 injections), before the beginning of oral corticotherapy.

Exclusion criteria :

* Age \< 18 years or whose disability warrants a guardianship
* All patients for whom corticoids prescribed \<20 mg per 24 hours or for an expected period \<3 months
* Intramuscular or intravenous sequential corticoids delivery, without associated per os corticoids.
* Any corticotherapies other than prednisone, prednisolone or methylprednisolone.
* Any corticotherapies with alternating doses
* Intravenous or intramuscular injection corticotherapy
* Patient who received corticoids at a dose \>20 mg / day, during 3 last years
* Allergy, hypersensitivity or cons-indication to corticoids
* The existence of diabetes before corticotherapy, because pre-existing diabetes requires specific follow-up treatment, such as sugars restrictions
* Uncontrolled hypertension (SBP ≥ 180mHg or DBP ≥ 110mHg)

Locations (1)

Paris, France