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Endothelial Function in Patients With Pulmonary Arterial Hypertension

CompletedNA

Sponsor: Universitätsklinikum Hamburg-Eppendorf

Conditions: Hypertension, Pulmonary, Pulmonary Arterial Hypertension, Pathophysiology, Genetics

Interventions: EndoPAT measurement, Blood Test

Countries: Germany

The objectives of the current study are to identify and evaluate new prognostic non-invasive and serological markers in patients with pulmonary hypertension. The focus will be on L-arginine metabolism and to clarify its influence on endothelial function.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: Yes

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* proven PH (by right heart catheterization, PAP \>25 mmHg, within last 12 months)
* age \>18 years
* Dana Point classification I or IV (all subgroups)
* declaration of consent

Exclusion Criteria:

* Pulmonary Hypertension not proven by right heart catheterization
* Eisenmenger's syndrome/reaction
* PH other than Dana Point I and IV
* alcohol or drug abuse
* non-compliance due to any cause (e.g. severe psychiatric disorder)

Locations (1)

Hamburg, Germany