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A Study Of PF-04449913 Administered Alone In Select Solid Tumors
A Study Of PF-04449913 Administered Alone In Select Solid Tumors

NCT01286467

CompletedPhase 1

Sponsor: Pfizer

Conditions: Solid Tumors

Interventions: PF-04449913

Countries: United States

This study examines the effect of a small molecule inhibitor to the Sonic Hedgehog pathway on select solid tumors.

Eligibility overview

Sex: ALL

Age: 18 Years to 99 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Histological or cytological diagnosis of advanced/metastatic solid tumor
* Adequate Bone Marrow Function
* Adequate Renal Function
* Adequate Liver Function

Exclusion Criteria:

* Patients with known symptomatic brain metastases requiring steroids
* Current active treatment on another clinical trial
* Major surgery or radiation therapy within 4-weeks of starting study treatment
Locations (9)
  • Los Angeles, California, United States
  • Los Angeles, California, United States
  • Los Angeles, California, United States
  • Los Angeles, California, United States
  • Aurora, Colorado, United States
  • Aurora, Colorado, United States
  • Aurora, Colorado, United States
  • Boston, Massachusetts, United States
  • Boston, Massachusetts, United States