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Early Lung Cancer Diagnosis in HIV Infected Population With an Important Smoking History With Low Dose CT: a Pilot Study
Early Lung Cancer Diagnosis in HIV Infected Population With an Important Smoking History With Low Dose CT: a Pilot Study

NCT01207986

CompletedNA

Sponsor: ANRS, Emerging Infectious Diseases

Conditions: Hiv Infection, Lung Cancer

Interventions: Low dose computed tomography (CT)

Countries: France

Early Lung Cancer diagnosis in a HIV-infected population with an important smoking history with low-dose CT: a pilot study: the HIV-CHEST study Objectives The main objective of this study is to evaluate the prevalence of lung cancers detected by low-dose computed tomography (CT) in a HIV-infected population with an important smoking history. Other objectives are (1) the evaluation of the types of lung cancers in this population, as well as (2) the staging of non small cell lung cancers, (3) the description of risk factors for all lung cancers, if they are numerous enough, and (4) the number of complications of diagnosis procedures during the study.

Eligibility overview

Sex: ALL

Age: 40 Years to 85 Years

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Age ≥ 40 years
* able to give written consent
* HIV positive serology
* Covered by French Social Security
* Nadir L TCD4 \< 350/µl
* Rate of LTCD4 \> 100/µl at inclusion
* Addiction to smoking \> 20 packages years, active person or deprived since \< 3 years

Exclusion Criteria:

* patients who suffered from comorbidity
* unaffiliated to the social healthy security french system
* Presence of an evolutionary cancer
* any evolutionary pathology classifying AIDS
* Pregnancy
* Recent lung infection (\< 2 months)
* Be under protection (saving) of justice
Locations (1)
  • Montpellier, France