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Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients

CompletedPhase 1

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Conditions: Cancer, Head and Neck Cancer, Pelvic Cancer, Nervous System Neoplasms, Thoracic Neoplasms

Interventions: Sunitinib, External Beam Radiation Therapy

Countries: United States

This study is using the combination of radiation and antiangiogenic agents (agents that destroy existing blood vessels) seems to be an approach to tumor cure.

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria

Inclusion Criteria:

* Minimum 2 week course of radiation therapy
* Solid tumors of the central nervous system, head and neck, thorax, and pelvis

Exclusion Criteria:

* Major surgery or radiation therapy within 4 weeks starting study treatment
* Grade 3 hemorrhage within 4 weeks

Locations (1)

Philadelphia, Pennsylvania, United States