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Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy
Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy

NCT00364351

CompletedPhase 3

Sponsor: Genzyme, a Sanofi Company

Conditions: Non Small Cell Lung Cancer

Interventions: Vandetanib, Erlotinib

Countries: United States, Argentina, Australia, Brazil, Canada, China, Denmark, France

To determine if ZD6474 a new investigational drug, is effective in treating Non Small Lung Cancer and if so, how it compares with another type of anti cancer therapy chemotherapy, Erlotinib

Eligibility overview

Sex: ALL

Age: 18 Years to —

Healthy volunteers: No

Study type: INTERVENTIONAL

Eligibility criteria
Inclusion Criteria:

* Confirmed locally advanced or metastatic NSCLC
* Failure of at least one but not more than two prior chemotherapy regimens

Exclusion Criteria:

* Prior treatment with erlotinib (Tarceva), gefitinib (IRESSA), sunitinib (Sutent), sorafenib (Nexavar)
* Chemotherapy or other type of anti cancer therapy within 4 weeks of study start
Locations (153)
  • Berkeley, California, United States
  • Los Angeles, California, United States
  • Santa Rosa, California, United States
  • Boynton Beach, Florida, United States
  • Fort Myers, Florida, United States
  • Jacksonville, Florida, United States
  • Port Saint Lucie, Florida, United States
  • Wichita, Kansas, United States
  • Lexington, Kentucky, United States
  • Louisville, Kentucky, United States
  • Metairie, Louisiana, United States
  • Baltimore, Maryland, United States
  • Columbia, Missouri, United States
  • St Louis, Missouri, United States
  • Latham, New York, United States
  • Hickory, North Carolina, United States
  • Canton, Ohio, United States
  • Cincinnati, Ohio, United States
  • Greenville, South Carolina, United States
  • Chattanooga, Tennessee, United States
  • Nashville, Tennessee, United States
  • Amarillo, Texas, United States
  • Garland, Texas, United States
  • Webster, Texas, United States
  • Fairfax, Virginia, United States
  • Norfolk, Virginia, United States
  • Richmond, Virginia, United States
  • Burien, Washington, United States
  • Yakima, Washington, United States
  • Ciudad de Buenos Aires, Argentina
  • + 123 more on CT.gov