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Results for “Roche”

A Study to Assess the Effects of RO6889450 (Ralmitaront) in Participants With Schizophrenia or Schizoaffective Disorder and Negative SymptomsTerminated
NCT03669640Phase 2Updated Aug 12, 2024
Sponsor: Hoffmann-La Roche
Schizophrenia, Schizoaffective Disorder
United States, Japan, Spain, Ukraine
A Multicentre, Parallel Arm, Open-label Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher Risk Patients With Diffuse Large B Cell Lymphoma (DLBCL)Active Not Recruiting
NCT04914741Phase 1, Phase 2Updated Aug 12, 2024
Sponsor: Peter MacCallum Cancer Centre, Australia
Diffuse Large B Cell Lymphoma · High-grade B-cell Lymphoma
Australia
A Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Enzalutamide in Participants With Metastatic Castration-Resistant Prostrate Cancer (mCRPC) After Failure of an Androgen Synthesis Inhibitor And Failure of, Ineligibility For, or Refusal of a Taxane RegimenCompleted
NCT03016312Phase 3Updated Aug 9, 2024
Sponsor: Hoffmann-La Roche
Prostatic Neoplasms, Castration-Resistant
United States, Australia, Austria, Belgium, Canada +16 more
A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal AdenocarcinomaTerminated
NCT03866239Phase 1Updated Aug 9, 2024
Sponsor: Hoffmann-La Roche
Colorectal Cancer
United States, Denmark, France, Spain
Investigate Safety, Tolerability, PK, PD and Efficacy of Risdiplam (RO7034067) in Infants With Type1 Spinal Muscular AtrophyCompleted
NCT02913482Phase 2Updated Aug 7, 2024
Sponsor: Hoffmann-La Roche
Muscular Atrophy, Spinal
United States, Belgium, Brazil, China, Croatia +11 more
A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Branch Retinal Vein OcclusionCompleted
NCT04740905Phase 3Updated Aug 6, 2024
Sponsor: Hoffmann-La Roche
Macular Edema · Branch Retinal Vein Occlusion
United States, Argentina, Australia, Austria, Brazil +17 more
A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Central Retinal or Hemiretinal Vein OcclusionCompleted
NCT04740931Phase 3Updated Aug 6, 2024
Sponsor: Hoffmann-La Roche
Macular Edema · Central Retinal Vein Occlusion · Hemiretinal Vein Occlusion
United States, Argentina, Australia, Austria, Brazil +17 more
A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic FunctionCompleted
NCT04226833Phase 1Updated Aug 2, 2024
Sponsor: Hoffmann-La Roche
Hepatic Insufficiency
Czechia, Hungary, Slovakia
Global Research Initiative for Patients Screening on MASHRecruiting
NCT05651724N/AUpdated Aug 1, 2024
Sponsor: Julius Clinical
MASH · MASLD · MASH With Fibrosis · Fibrosis, Liver
Belgium, Czechia, France, Germany, Greece +5 more
Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung CancerCompleted
NCT04622228Phase 2Updated Jul 29, 2024
Sponsor: Hoffmann-La Roche
Carcinoma, Small Cell Lung
China
Ipatasertib Plus Non-Taxane Chemotherapy for Advanced or Metastatic Triple-Negative Breast CancerCompleted
NCT04464174Phase 2Updated Jul 26, 2024
Sponsor: MedSIR
Triple Negative Breast Cancer
Portugal, Spain
Southeast Netherlands Advanced Metastatic Breast Cancer RegistryRecruiting
NCT03577197N/AUpdated Jul 23, 2024
Sponsor: Academisch Ziekenhuis Maastricht
Advanced Breast Cancer · Metastatic Breast Cancer
Netherlands
A Study of Bevacizumab, Carboplatin, and Paclitaxel or Pemetrexed With or Without Atezolizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer (IMpower151)Completed
NCT04194203Phase 3Updated Jul 19, 2024
Sponsor: Hoffmann-La Roche
Carcinoma, Non-Small-Cell Lung
China
A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung CancerCompleted
NCT04028050Phase 3Updated Jul 16, 2024
Sponsor: Hoffmann-La Roche
Small Cell Lung Carcinoma
Italy
Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy VolunteersCompleted
NCT04729309Phase 1Updated Jul 15, 2024
Sponsor: Hoffmann-La Roche
Healthy Volunteers
United Kingdom
An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care TreatmentCompleted
NCT04165135N/AUpdated Jul 12, 2024
Sponsor: Hoffmann-La Roche
Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor · Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor · Haemophilia A
Italy
A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax in Combination With Polatuzumab Vedotin Plus Rituximab (R) and Cyclophosphamide, Doxorubicin, Prednisone (CHP) in Participants With Untreated BCL-2 Immunohistochemistry (IHC)-Positive Diffuse Large B-Cell Lymphoma (DLBCL)Terminated
NCT04790903Phase 1Updated Jul 11, 2024
Sponsor: Hoffmann-La Roche
Lymphoma, Large B-Cell, Diffuse
United States, France, Italy, Spain
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy ParticipantsCompleted
NCT04475848Phase 1Updated Jul 10, 2024
Sponsor: Hoffmann-La Roche
Autistic Disorder · Autism Spectrum Disorder · Child Development Disorders, Pervasive · Mental Disorders
United Kingdom
Study of RO7515629 in Participants With HLA-G Positive Solid TumorsTerminated
NCT05769959Phase 1Updated Jul 9, 2024
Sponsor: Hoffmann-La Roche
Renal Cell Carcinoma · Non-small Cell Lung Cancer · Pancreatic Adenocarcinoma · Colorectal Cancer
United States
Efficacy and Safety Study of a New Therapeutic Strategy in the Treatment of Extended-Disease Small-Cell Lung CancerCompleted
NCT04730999Phase 2Updated Jul 5, 2024
Sponsor: Gruppo Oncologico Italiano di Ricerca Clinica
Small Cell Lung Cancer
Italy
Epidemiological Landscape of Cervical Cancer in Latin AmericaActive Not Recruiting
NCT04947605N/AUpdated Jul 5, 2024
Sponsor: Latin American Cooperative Oncology Group
Uterine Cervical Neoplasms
Brazil
A Study of Atezolizumab With or Without Bevacizumab in Combination With Cisplatin Plus Gemcitabine in Patients With Untreated, Advanced Biliary Tract CancerCompleted
NCT04677504Phase 2Updated Jul 3, 2024
Sponsor: Hoffmann-La Roche
Biliary Tract Cancer
United States, China, Hong Kong, Italy, Poland +8 more
Doxorubicin Alone Versus Atezolizumab Alone Versus Doxorubicin and Atezolizumab in Recurrent Cervical CancerUnknown
NCT03340376Phase 2Updated Jul 3, 2024
Sponsor: Universitaire Ziekenhuizen KU Leuven
Cervical Cancer
Belgium
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH)Recruiting
NCT06446271N/AUpdated Jul 3, 2024
Sponsor: NHS Greater Glasgow and Clyde
Cardiomyopathies · Genetic Predisposition · Cardiomyopathy, Primary
United Kingdom
European Cardiac Resynchronisation Therapy SurveyCompleted
NCT01185392N/AUpdated Jun 27, 2024
Sponsor: Helse Stavanger HF
Heart Failure

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