Explore

Search ClinicalTrials.gov

Find trials by condition, intervention, sponsor, or location. Filter by status, phase, and study type — or enter an NCT ID to jump straight to a trial.

Find trials by sponsor or company

Search by sponsors

RecruitingPhase IIIPhase III recruiting

StatusPhaseStudy typeSort

Results for “Roche”

A Study of Participants With Initially Unresectable Hepatocellular Carcinoma That is Treated With Atezolizumab and Bevacizumab Plus Transarterial ChemoembolizationCompleted
NCT06503250N/AUpdated Mar 21, 2025
Sponsor: Hoffmann-La Roche
Unresectable Hepatocellular Carcinoma
China
PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study)Completed
NCT04484636NAUpdated Mar 20, 2025
Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Hepatocellular Cancer · Cholangiocarcinoma · Gallbladder Cancer · Pancreatic Cancer
Germany
18F-Dihydroxyphenylalanine (DOPA) Positron Emission Tomography (PET) Study to Explore Dopamine Synthesis Capacity in the Whole Striatum After 2 Weeks of Treatment With Ralmitaront or Placebo in Participants With SchizophreniaCompleted
NCT06880328Phase 1Updated Mar 17, 2025
Sponsor: Hoffmann-La Roche
Schizophrenia
United States
Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).Recruiting
NCT06663098Phase 2Updated Mar 13, 2025
Sponsor: Gruppo Oncologico Italiano di Ricerca Clinica
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Italy
Prognostic Role of Circulating Tumor DNA in Resectable Pancreatic CancerActive Not Recruiting
NCT04246203N/AUpdated Mar 11, 2025
Sponsor: Ludwig-Maximilians - University of Munich
Pancreas Cancer
Germany
Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation TherapyTerminated
NCT05137899Phase 2Updated Mar 11, 2025
Sponsor: Ontario Clinical Oncology Group (OCOG)
Hepatocellular Carcinoma · Portal Vein Tumour Thrombosis
Canada
A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine CarcinomasCompleted
NCT05619744Phase 1Updated Mar 10, 2025
Sponsor: Hoffmann-La Roche
Small Cell Lung Cancer · Neuroendocrine Carcinoma
United States, Denmark, Japan, Poland, Spain
Preoperative MPDL3280A in Transitional Cell Carcinoma of the BladderCompleted
NCT02662309Phase 2Updated Mar 10, 2025
Sponsor: Queen Mary University of London
Bladder Cancer
France, Netherlands, Spain, United Kingdom
A Study To Evaluate Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Patients With Generalized Myasthenia GravisTerminated
NCT04963270Phase 3Updated Feb 28, 2025
Sponsor: Hoffmann-La Roche
Generalized Myasthenia Gravis
United States, Argentina, Australia, Brazil, Canada +12 more
A Prospective, Randomized Multicenter, Open-label Comparison of Preoperative Trastuzumab Emtansine (T-DM1) With or Without Standard Endocrine Therapy vs. Trastuzumab With Standard Endocrine Therapy Given for Twelve Weeks in Patients With Operable HER2+/HR+ Breast Cancer Within the ADAPT Protocol.Completed
NCT01745965Phase 2Updated Feb 27, 2025
Sponsor: Women's Cancer Study Group GmbH
Breast Cancer
Germany
A Prospective, Randomized Multicenter, Open-label Comparison of Preoperative Combination of Trastuzumab and Pertuzumab With or Without Concurrent Taxane Chemotherapy Given for Twelve Weeks in Patients With Operable HER2+/HR- Breast Cancer Within the ADAPT ProtocolCompleted
NCT01817452Phase 2Updated Feb 26, 2025
Sponsor: Women's Cancer Study Group GmbH
Breast Cancer
Germany
A Study Investigating [14C]-Labeled RO7269162 in Healthy Male ParticipantsCompleted
NCT06733298Phase 1Updated Feb 25, 2025
Sponsor: Hoffmann-La Roche
Healthy Volunteers
Netherlands
Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Metastatic Urothelial CarcinomaCompleted
NCT02807636Phase 3Updated Feb 24, 2025
Sponsor: Hoffmann-La Roche
Urothelial Carcinoma
United States, Australia, Belgium, Bosnia and Herzegovina, Brazil +30 more
Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc)Recruiting
NCT03548428Phase 2Updated Feb 19, 2025
Sponsor: Centre Antoine Lacassagne
Sarcoma · Radiosurgery
France
Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma PatientsRecruiting
NCT02622581N/AUpdated Feb 18, 2025
Sponsor: AIO-Studien-gGmbH
Metastatic Non-small Cell Lung Cancer (NSCLC) · Non-small Cell Lung Cancer Metastatic · Non-small Cell Lung Cancer Stage II · Non Small Cell Lung Cancer Stage III
Germany
Neoadjuvant Endocrine Therapy +/- the PI3K Inhibitor Inavolisib in HER2+, HR+, PIK3CA Mutant Early Breast CancerRecruiting
NCT05306041Phase 2Updated Feb 17, 2025
Sponsor: GBG Forschungs GmbH
HER2-positive Breast Cancer
Germany, Italy
Serum Neurofilament Light in Multiple SclerosisActive Not Recruiting
NCT06282081N/AUpdated Feb 14, 2025
Sponsor: Dent Neuroscience Research Center
Multiple Sclerosis · Relapsing Remitting Multiple Sclerosis
United States
ATALANTE: Atezolizumab vs Placebo Phase III Study in Late Relapse Ovarian Cancer Treated With Chemotherapy+BevacizumabCompleted
NCT02891824Phase 3Updated Feb 11, 2025
Sponsor: ARCAGY/ GINECO GROUP
Ovarian Cancer
Austria, Belgium, Czechia, France, Germany +2 more
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic MutationTerminated
NCT06424236Phase 2, Phase 3Updated Feb 4, 2025
Sponsor: Washington University School of Medicine
Alzheimers Disease · Dementia · Alzheimers Disease, Familial
United States, Australia, France, Puerto Rico, Spain +1 more
Acceptability, Feasibility, Safety and Efficacy of a Optimized Rehabilitation Program for Treated Patients With Spinal Muscular Atrophy (SMA).Active Not Recruiting
NCT06419322NAUpdated Feb 3, 2025
Sponsor: University of Oxford
Spinal Muscular Atrophy
United Kingdom
Thoracic RadiothErapy With Atezolizumab in Small Cell lUng canceR Extensive DiseaseCompleted
NCT04462276Phase 2Updated Jan 30, 2025
Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Small Cell Lung Cancer Extensive Stage · Thoracic Radiotherapy
Austria, Germany
A 12-Week Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)Completed
NCT04299464Phase 2Updated Jan 28, 2025
Sponsor: Hoffmann-La Roche
Autism Spectrum Disorder (ASD)
United States, Canada, Italy, Spain
A Study of Elecsys® Troponin T hs Gen 6 in Participants With Symptoms of Acute Coronary SyndromeCompleted
NCT06734117N/AUpdated Jan 24, 2025
Sponsor: Hoffmann-La Roche
Acute Coronary Syndrome · Myocardial Infarction
United States, Austria, Bulgaria, China, Germany +6 more
Signatures of Response and Resistance to Mosunetuzomab in Follicular Lymphomas (FL)Completed
NCT05529524N/AUpdated Jan 24, 2025
Sponsor: The Lymphoma Academic Research Organisation
Follicular Lymphoma
France
NOSTRA-Feasibility Study: A Study Looking at Ultrasound Guided Biopsies for Breast CancerActive Not Recruiting
NCT04118192N/AUpdated Jan 24, 2025
Sponsor: University of Birmingham
Breast Cancer
United Kingdom

Previous page Next page