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Results for “Roche”

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell MalignanciesActive Not Recruiting
NCT06014762Phase 1Updated May 7, 2026
Sponsor: Poseida Therapeutics, Inc.
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified · High-grade B-cell Lymphoma · Primary Mediastinal Large B-cell Lymphoma (PMBCL) · Transformed Follicular Lymphoma (tFL)
United States
Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)Recruiting
NCT04635891N/AUpdated May 7, 2026
Sponsor: University of Kansas Medical Center
FSHD
United States, Brazil, Canada, United Kingdom
Obinutuzumab in Marginal Zone LymphomaActive Not Recruiting
NCT03322865Phase 2Updated May 6, 2026
Sponsor: Christian Buske
Marginal Zone Lymphoma
Germany
A Study to Learn About the Effects of Two Study Medicines (Maplirpacept [PF-07901801] And Glofitamab) When Given Together In People With Relapsed Or Refractory Diffuse Large B Cell Lymphoma.Terminated
NCT05896163Phase 1, Phase 2Updated May 6, 2026
Sponsor: Pfizer
Diffuse Large B-Cell Lymphoma
United States, Israel, Japan, Turkey (Türkiye)
Biomarkers to Classify Heart FailureActive Not Recruiting
NCT02347722N/AUpdated May 6, 2026
Sponsor: Ottawa Heart Institute Research Corporation
Heart Failure
Canada
Biomarker Guided Discharge of Heart Failure PatientsRecruiting
NCT03103932NAUpdated May 6, 2026
Sponsor: Ottawa Heart Institute Research Corporation
Heart Failure; With Decompensation
Canada
A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and NeckCompleted
NCT04665843Phase 2Updated May 5, 2026
Sponsor: Hoffmann-La Roche
Squamous Cell Carcinoma of Head and Neck
United States, Czechia, France, Greece, Hungary +8 more
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's DiseaseRecruiting
NCT06826612Phase 1, Phase 2Updated May 5, 2026
Sponsor: Hoffmann-La Roche
Huntington Disease
United States
Deciphering Antitumour Response and Resistance With INtratumour HeterogeneityCompleted
NCT02314481Phase 2Updated May 4, 2026
Sponsor: University College, London
Non-small Cell Lung Cancer
United Kingdom
A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household ContactsRecruiting
NCT06094010Phase 3Updated May 1, 2026
Sponsor: Hoffmann-La Roche
Influenza
United States, Bulgaria, Poland, Spain
Pediatric Prospective Personalized Immune and Target Identification TrialCompleted
NCT04859543NAUpdated May 1, 2026
Sponsor: Masaryk University
Central Nervous System Neoplasms · Pediatric Cancer · GEN1 Gene Mutation · Tumor, Brain
Austria, Czechia
Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)Active Not Recruiting
NCT04608318Phase 3Updated Apr 30, 2026
Sponsor: German CLL Study Group
Chronic Lymphoid Leukemia
Austria, Belgium, Denmark, Finland, Germany +8 more
A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD)Completed
NCT05075824Phase 2Updated Apr 30, 2026
Sponsor: Hoffmann-La Roche
Sickle Cell Disease
United States, Brazil, France, Italy, Kenya +6 more
TRIMPACT: Real-World First-Line Atezolizumab Use in Stage IV NSCLC With PD-L1 ≥50%Recruiting
NCT07279402N/AUpdated Apr 30, 2026
Sponsor: Antalya Training and Research Hospital
NSCLC Stage IV · PD-L1 Gene Mutation · Atezolizumab · Real World Study
Turkey (Türkiye)
PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast CancerActive Not Recruiting
NCT06172127Phase 2Updated Apr 29, 2026
Sponsor: MedSIR
HER2-positive Breast Cancer
United States, France, Germany, Italy, Spain
Chemotherapy-Free pCR-Guided Strategy With Trastuzumab-pertuzumab and T-DM1 in HER2-positive Early Breast CancerActive Not Recruiting
NCT04733118Phase 2Updated Apr 29, 2026
Sponsor: MedSIR
Early Breast Cancer
Bulgaria, Germany, Hungary, Italy, Spain
Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Chinese Pediatric Participants 1 to <12 Years of Age With Influenza SymptomsCompleted
NCT06774859Phase 3Updated Apr 27, 2026
Sponsor: Hoffmann-La Roche
Influenza
China
Biomarkers in Perioperative ManagementRecruiting
NCT05199025N/AUpdated Apr 27, 2026
Sponsor: St. Antonius Hospital
Postoperative Complications · Quality of Life · Death
Netherlands
Canadian CHO-KLAT/H-FIT Study - Quality of Life of, and Burden of Caring for, Persons With HemophiliaCompleted
NCT06191068N/AUpdated Apr 24, 2026
Sponsor: The Hospital for Sick Children
Hemophilia
Canada
P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple MyelomaActive Not Recruiting
NCT04960579Phase 1Updated Apr 24, 2026
Sponsor: Poseida Therapeutics, Inc.
Multiple Myeloma
United States
Use of Gender, Age, Alfa-fetoprotein (AFP), and Des-gamma-carboxyprothrombin (PIVKA-II) or GAAD Score in Addition to Ultrasound for Surveillance of People At-risk for Developing Hepatocellular Carcinoma in Asia in Order to Detect Early Liver CancerEnrolling By Invitation
NCT07298577NAUpdated Apr 24, 2026
Sponsor: Siriraj Hospital
Liver Cirrhosis · Hepatitis B, Chronic · Hepatitis C, Chronic · Carcinoma, Hepatocellular
Thailand
Ending the HIV Epidemic Through Point-of-Care Technologies (EHPOC)Completed
NCT04793750NAUpdated Apr 23, 2026
Sponsor: Johns Hopkins University
HIV Infections · Syphilis
United States
Study Evaluating the Interest of Vismodegib as Neo-adjuvant Treatment of Basal Cell Carcinoma (BCC)Completed
NCT02667574Phase 2Updated Apr 22, 2026
Sponsor: University Hospital, Lille
Basal Cell Carcinoma
France
Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the CervixCompleted
NCT03556839Phase 3Updated Apr 21, 2026
Sponsor: Grupo Español de Investigación en Cáncer de Ovario
Carcinoma of the Cervix, Stage IVB
United States, France, Germany, Italy, Japan +3 more
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)Recruiting
NCT06884618Phase 1Updated Apr 21, 2026
Sponsor: Hoffmann-La Roche
Neoplasms
United States, Australia, Canada, China, Denmark +5 more

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