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A Long-term Extension Study of PCI-32765 (Ibrutinib)Recruiting
NCT01804686Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma · Mantle Cell Lymphoma · Follicular Lymphoma
United States, Argentina, Australia, Belgium, Brazil +25 more
Surgery vs. Radical Chemoradiotherapy for Esophageal SCC After Neoadjuvant ImmunochemotherapyRecruiting
NCT07629817Phase 3Updated Jul 31, 2026
Sponsor: Henan Cancer Hospital
Esophageal Squamous Cell Carcinoma
China
This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.Recruiting
NCT06616025Phase 3Updated Jul 31, 2026
Sponsor: Neuraptive Therapeutics Inc.
Peripheral Nerve Injury Upper Limb · Peripheral Nerve Injury (PNI)
United States
A Trial of the Efficacy and Safety of SEP-363856 in Acutely Psychotic Participants With SchizophreniaRecruiting
NCT06894212Phase 3Updated Jul 31, 2026
Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Schizophrenia
United States, Japan
A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia GravisRecruiting
NCT05265273Phase 2, Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Myasthenia Gravis
United States, Japan, Netherlands, Poland
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)Recruiting
NCT07252232Phase 3Updated Jul 31, 2026
Sponsor: Revolution Medicines, Inc.
Pancreatic Cancer · PDAC · PDAC - Pancreatic Ductal Adenocarcinoma · Resectable Pancreatic Ductal Adenocarcinoma (PDAC)
United States, France, Germany, Italy, Japan +4 more
JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCCRecruiting
NCT04892173Phase 3Updated Jul 31, 2026
Sponsor: Johnson & Johnson Enterprise Innovation Inc.
Carcinoma, Squamous Cell
United States, Austria, Belgium, Brazil, Bulgaria +22 more
A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic ArthritisRecruiting
NCT06807424Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Arthritis, Psoriatic
United States, Argentina, Australia, Brazil, Bulgaria +19 more
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence StudyRecruiting
NCT06713616Phase 3Updated Jul 31, 2026
Sponsor: Yale University
Depression
United States
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive DisorderRecruiting
NCT07227454Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Depressive Disorder, Major
United States, Brazil, Hungary, Italy, Romania +2 more
Caffeine Consumption and Rate Control in Permanent Atrial FIBrillation: The CAFIB TrialRecruiting
NCT07738523Phase 2, Phase 3Updated Jul 31, 2026
Sponsor: Hospital Universitario Getafe
Atrial Fibrillation (AF) · Permanent Atrial Fibrillation · Coffee Consumption · Caffeine Abuse
Spain
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07196748Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Colitis, Ulcerative
United States, Argentina, Australia, Belgium, Brazil +23 more
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck CancerRecruiting
NCT07276399Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Squamous Cell Carcinoma of Head and Neck
United States, Australia, Austria, Belgium, Brazil +17 more
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)Recruiting
NCT06852222Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Leukemia, Myeloid, Acute
United States, Australia, Austria, Belgium, Brazil +20 more
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive DisorderRecruiting
NCT05850689Phase 3Updated Jul 31, 2026
Sponsor: Intra-Cellular Therapies, Inc.
Major Depressive Disorder
United States, Bulgaria, France, India, Lithuania +2 more
Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent Breast Cancer Using Genomic TestsRecruiting
NCT07106632Phase 3Updated Jul 31, 2026
Sponsor: UNICANCER
Early Breast Cancer · Premenopausal Breast Cancer · HR+/HER2- Breast Cancer
Belgium, France, Greece, Ireland, Italy +2 more
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive DisorderRecruiting
NCT07573176Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Depressive Disorder, Major
United States, Brazil, Malaysia, Taiwan
Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck CancersRecruiting
NCT04747054Phase 3Updated Jul 31, 2026
Sponsor: UNICANCER
Squamous Cell Carcinoma of Head and Neck
France
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric CancerRecruiting
NCT06901531Phase 3Updated Jul 31, 2026
Sponsor: Astellas Pharma Global Development, Inc.
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer · Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer · Metastatic Gastric Adenocarcinoma or Cancer · Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
United States, Australia, Belgium, Brazil, Chile +17 more
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple MyelomaRecruiting
NCT07258511Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Multiple Myeloma
United States, Australia, Canada, China, France +9 more
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia GravisRecruiting
NCT07217587Phase 3Updated Jul 31, 2026
Sponsor: Janssen Research & Development, LLC
Myasthenia Gravis
United States, Israel, Switzerland
Suzetrigine in Total Hip ArthroplastyRecruiting
NCT07226700Phase 3Updated Jul 30, 2026
Sponsor: Hospital for Special Surgery, New York
Total Hip Arthroplasty (THA) · Total Hip Arthroplasty \(THA\) · Total Hip Replacement · Total Hip Replacement Surgery
United States
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate CancerRecruiting
NCT07225946Phase 3Updated Jul 30, 2026
Sponsor: Janssen Research & Development, LLC
Prostatic Neoplasms, Castration-Resistant
United States, Australia, Belgium, Brazil, Canada +12 more
Assessment of a New Enhanced Xenograft in Open Maxillary Sinus AugmentationRecruiting
NCT07737704Phase 2, Phase 3Updated Jul 30, 2026
Sponsor: Misr International University
Maxillary Sinus Floor Augmentation · Maxillary Sinus Elevation · Bone Augmentation
Egypt
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)Recruiting
NCT07517263Phase 3Updated Jul 30, 2026
Sponsor: Novartis Pharmaceuticals
Cardiovascular Disease and Lipoprotein(a)
United States, Argentina, Australia, Austria, Belgium +34 more

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