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A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic CancerRecruiting
NCT07409272Phase 3Updated Jul 27, 2026
Sponsor: Astellas Pharma Global Development, Inc.
Pancreatic Cancer · Metastatic Pancreatic Cancer · Metastatic Pancreatic Adenocarcinoma
United States, Japan
Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRTRecruiting
NCT05399537Phase 3Updated Jul 27, 2026
Sponsor: Vantive Health LLC
Regional Citrate Anticoagulation (RCA) · Continuous Renal Replacement Therapy (CRRT) · Acute Kidney Injury (AKI)
United States
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASHRecruiting
NCT07221227Phase 3Updated Jul 27, 2026
Sponsor: GlaxoSmithKline
Non-alcoholic Fatty Liver Disease
United States, Australia, Canada, Hong Kong, Japan +4 more
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research DesignRecruiting
NCT07398417Phase 3Updated Jul 24, 2026
Sponsor: Axsome Therapeutics, Inc.
Fibromyalgia
United States
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial HypercholesterolemiaRecruiting
NCT06597006Phase 3Updated Jul 24, 2026
Sponsor: Novartis Pharmaceuticals
Familial Hypercholesterolemia - Homozygous
United States, Austria, China, Germany, Greece +6 more
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)Recruiting
NCT06136624Phase 3Updated Jul 24, 2026
Sponsor: Merck Sharp & Dohme LLC
Prostate Cancer Metastatic
United States, Argentina, Australia, Austria, Brazil +31 more
ACP-204 in Adults With Alzheimer's Disease PsychosisRecruiting
NCT06159673Phase 2, Phase 3Updated Jul 24, 2026
Sponsor: ACADIA Pharmaceuticals Inc.
Alzheimer's Disease Psychosis
United States, Brazil, Bulgaria, Chile, Czechia +7 more
A Study of BL-M07D1 Versus Physician's Choice of Chemotherapy in Patients With HER2-expressing Locally Advanced or Metastatic Biliary Tract Cancer After Platinum-containing Chemotherapy FailureRecruiting
NCT07606599Phase 3Updated Jul 24, 2026
Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.
Biliary Tract Cancer
China
Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of VG081821AC Tablets in Patients With Early to Mid-stage Parkinson's DiseaseRecruiting
NCT07725562Phase 2, Phase 3Updated Jul 24, 2026
Sponsor: Zhejiang Vimgreen Pharmaceuticals, Ltd.
Parkinson Disease (PD)
China
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung CancerRecruiting
NCT06712355Phase 3Updated Jul 24, 2026
Sponsor: BioNTech SE
Extensive-stage Small-cell Lung Cancer
United States, Australia, China, France, Germany +9 more
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin AnalogsRecruiting
NCT06930625Phase 3Updated Jul 24, 2026
Sponsor: Debiopharm International SA
Acromegaly
United States, Austria, Belgium, Brazil, Bulgaria +16 more
Efficacy, Safety and Tolerability of Givinostat in Non-ambulant Patients With Duchenne Muscular DystrophyRecruiting
NCT05933057Phase 3Updated Jul 24, 2026
Sponsor: Italfarmaco
Duchenne Muscular Dystrophy
Belgium, Canada, Czechia, France, Germany +7 more
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using SolriamfetolRecruiting
NCT07484217Phase 3Updated Jul 24, 2026
Sponsor: Axsome Therapeutics, Inc.
Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
United States
Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum ThrombosisRecruiting
NCT07140211Phase 3Updated Jul 24, 2026
Sponsor: Marc Blondon
Venous Thromboembolism (VTE) · Postpartum
Switzerland
Program for Rifampicin-Resistant Disease With Stratified Medicine for TuberculosisRecruiting
NCT06441006Phase 2, Phase 3Updated Jul 24, 2026
Sponsor: University of California, San Francisco
Tuberculosis, Pulmonary · Tuberculosis, Multidrug-Resistant · Tuberculosis, MDR
Mongolia, Pakistan, Peru, Uganda, Vietnam
Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's DiseaseRecruiting
NCT04528082Phase 3Updated Jul 24, 2026
Sponsor: Amgen
Behçet Disease
France, Greece, Israel, Italy, Spain +3 more
Comparison of Alpha Blockers (Terazosin and Tamsulosin) in Reducing Ureteral Stent Related SymptomsRecruiting
NCT06966804Phase 3Updated Jul 24, 2026
Sponsor: Penang Hospital, Malaysia
Stent Related Symptoms
Malaysia
Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)Recruiting
NCT05722938Phase 3Updated Jul 24, 2026
Sponsor: Biotest
Community-acquired Pneumonia
United States, Argentina, Australia, Austria, Belgium +13 more
Phase III Study of HRS-5635 in Nucleos(t)Ide Analogue-suppressed HBeAg-negative Patients With Chronic Hepatitis BRecruiting
NCT07606950Phase 3Updated Jul 24, 2026
Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd.
Nucleos(t)Ide Analogue-suppressed HBeAg-negative Patients With Chronic Hepatitis B
China
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)Recruiting
NCT06966401Phase 3Updated Jul 24, 2026
Sponsor: Neurocrine Biosciences
Major Depressive Disorder
United States, Belgium, Bulgaria, Canada, Croatia +15 more
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)Recruiting
NCT06929273Phase 3Updated Jul 24, 2026
Sponsor: Bristol-Myers Squibb
Bipolar Disorder Type I With Mania
United States, Argentina, Australia, Bulgaria, China +15 more
A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)Recruiting
NCT06449651Phase 3Updated Jul 24, 2026
Sponsor: Janssen Research & Development, LLC
Thrombocytopenia, Neonatal Alloimmune
Belgium, Brazil, France, Hungary, Israel +7 more
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)Recruiting
NCT07196501Phase 3Updated Jul 24, 2026
Sponsor: Neurocrine Biosciences
Major Depressive Disorder
United States, Australia, Bulgaria, Canada, Estonia +6 more
Shortened Regimen for Drug-susceptible TB in ChildrenRecruiting
NCT06253715Phase 3Updated Jul 24, 2026
Sponsor: Johns Hopkins University
Tuberculosis · Tuberculosis, Pulmonary · Tuberculosis, Lymph Node · Mycobacterium Tuberculosis
India, Indonesia, Mozambique, South Africa, Uganda +2 more
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)Recruiting
NCT06568367Phase 3Updated Jul 24, 2026
Sponsor: Axsome Therapeutics, Inc.
Excessive Sleepiness · Shift-work Disorder
United States, Canada

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