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Optimizing Pain Treatment in Children On Mechanical VentilationRecruiting
NCT06994442Phase 3Updated Jul 30, 2026
Sponsor: Weill Medical College of Cornell University
Mechanical Ventilation · Pediatric Acute Respiratory Failure · Analgesics, Opioid · Sedation and Analgesia
United States
Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced MucositisRecruiting
NCT07736495Phase 2, Phase 3Updated Jul 30, 2026
Sponsor: Ain Shams University
Colorectal Cancer
Egypt
A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it WorksRecruiting
NCT05744921Phase 3Updated Jul 30, 2026
Sponsor: Regeneron Pharmaceuticals
Paroxysmal Nocturnal Hemoglobinuria
Canada, Colombia, Hungary, India, Italy +14 more
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)Recruiting
NCT06126224Phase 3Updated Jul 30, 2026
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Psychosis Associated With Alzheimer's Disease
United States, Belgium, Canada, Chile, China +9 more
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast CancerRecruiting
NCT06380751Phase 3Updated Jul 30, 2026
Sponsor: AstraZeneca
Advanced Breast Cancer
United States, Argentina, Australia, Austria, Brazil +24 more
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)Recruiting
NCT06585787Phase 3Updated Jul 30, 2026
Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Alzheimer Disease
United States, Argentina, Belgium, Brazil, Bulgaria +20 more
Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant SchizophreniaRecruiting
NCT07184619Phase 3Updated Jul 30, 2026
Sponsor: Newron Pharmaceuticals SPA
Treatment-resistant Schizophrenia
United States, India, Malaysia
D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract CancerRecruiting
NCT06622057Phase 3Updated Jul 30, 2026
Sponsor: InnoPharmax Inc.
Biliary Tract Cancer (BTC)
United States, Taiwan
A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular TreatmentRecruiting
NCT07201129Phase 3Updated Jul 30, 2026
Sponsor: Viatris Innovation GmbH
Nephritis, Lupus · Lupus Erythematosus, Systemic
United States
Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma PatientsRecruiting
NCT07336277Phase 3Updated Jul 30, 2026
Sponsor: Emory University
Orthopedic Trauma · Sleep Quality
United States
Evaluate the Efficacy of Using Modified Qing-Ying Decoction in Atopic Dermatitis ChildrenRecruiting
NCT04419584Phase 2, Phase 3Updated Jul 30, 2026
Sponsor: Chinese University of Hong Kong
Atopic Dermatitis
Hong Kong
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T CellsRecruiting
NCT03435796Phase 2, Phase 3Updated Jul 30, 2026
Sponsor: Celgene
Neoplasms
United States, Australia, Austria, Belgium, Canada +15 more
Study of Lenacapavir, Teropavimab, and Zinlirvimab in Virologically Suppressed Adults With HIV-1 on Stable Oral Treatment RegimensRecruiting
NCT07683000Phase 3Updated Jul 30, 2026
Sponsor: Gilead Sciences
HIV-1-infection
United States
A Study of Dotinurad Versus Allopurinol in Tophaceous GoutRecruiting
NCT07089888Phase 3Updated Jul 30, 2026
Sponsor: Crystalys Therapeutics
Tophaceous Gout
United States
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GlioblastomaRecruiting
NCT03970447Phase 2, Phase 3Updated Jul 30, 2026
Sponsor: Global Coalition for Adaptive Research
Glioblastoma
United States, Australia, Canada, France, Germany +1 more
Discontinuation One Week Recommendations for GLP-1 Receptor Agonists Prior to Esophagogastroduodenoscopy.Recruiting
NCT07736911Phase 3Updated Jul 30, 2026
Sponsor: Fu Jen Catholic University Hospital
GLP-1
Taiwan
Study of Ravulizumab in Pediatric Participants With Primary IgANRecruiting
NCT07024563Phase 3Updated Jul 30, 2026
Sponsor: Alexion Pharmaceuticals, Inc.
IgAN · IgAVN · Immunoglobulin A Nephropathy · Immunoglobulin A Vasculitis Associated Nephritis
United States, China, Italy, Japan, South Korea +2 more
High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)Recruiting
NCT05589181Phase 3Updated Jul 30, 2026
Sponsor: Rutgers, The State University of New Jersey
Opioid Use Disorder
United States
Unipolar Versus Bipolar Interlocking in Humeral Shaft Fractures in AdultsRecruiting
NCT05877014Phase 3Updated Jul 30, 2026
Sponsor: Centre Hospitalier Universitaire Dijon
Humeral Shaft Fracture
France
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightRecruiting
NCT07564414Phase 3Updated Jul 30, 2026
Sponsor: Novo Nordisk A/S
Obesity · Type 2 Diabetes
United States, Argentina, Australia, Austria, Belgium +14 more
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)Recruiting
NCT06170788Phase 3Updated Jul 30, 2026
Sponsor: Merck Sharp & Dohme LLC
Non-small Cell Lung Cancer (NSCLC)
United States, Argentina, Australia, Brazil, Canada +21 more
A Study of Dotinurad Versus Allopurinol in Participants With GoutRecruiting
NCT07089875Phase 3Updated Jul 30, 2026
Sponsor: Crystalys Therapeutics
Gout
United States, Poland, Spain
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia GravisRecruiting
NCT07039916Phase 3Updated Jul 30, 2026
Sponsor: Immunovant Sciences GmbH
Generalized Myasthenia Gravis
United States, Argentina, Czechia, Denmark, Georgia +10 more
Reducing Filth Fly Populations and Transmission of Diarrhoeal Pathogens in Harsh SettingsRecruiting
NCT07272122Phase 3Updated Jul 29, 2026
Sponsor: The Mentor Initiative
Diarrheal Diseases
South Sudan
Colchicine for Autoimmune and Subacute ThyroiditisRecruiting
NCT07571681Phase 2, Phase 3Updated Jul 29, 2026
Sponsor: Mansoura University
Hashimoto Thyroiditis · Subacute Thyroiditis · Thyroiditis
Egypt, Saudi Arabia

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