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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive SubjectsRecruiting
NCT05232916Phase 3Updated Aug 6, 2026
Sponsor: Greenwich LifeSciences, Inc.
Breast Cancer
United States, Belgium, France, Germany, Ireland +5 more
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder CancerRecruiting
NCT06995677Phase 2Updated Aug 6, 2026
Sponsor: Tyra Biosciences, Inc
Low-grade NMIBC · FGFR Gene Amplification · FGFR Gene Alterations · FGFR3 Gene Alteration
United States, Australia, Italy, Spain
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 OverexpressionRecruiting
NCT07023627Phase 2Updated Aug 6, 2026
Sponsor: Incyte Corporation
Ovarian Cancer
United States, Australia, Belgium, Japan, Puerto Rico +3 more
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's DiseaseRecruiting
NCT07169578Phase 3Updated Aug 6, 2026
Sponsor: Hoffmann-La Roche
Alzheimers Disease
United States, Argentina, Brazil, Canada, China +8 more
BOOM-IBD2 Pivotal Clinical TrialRecruiting
NCT06571669NAUpdated Aug 6, 2026
Sponsor: Boomerang Medical
Ulcerative Colitis · Inflammatory Bowel Diseases
United States
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaRecruiting
NCT07213973Phase 2Updated Aug 6, 2026
Sponsor: Incyte Corporation
Hidradenitis Suppurativa (HS)
United States, Canada
Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress SyndromeRecruiting
NCT06776783Phase 3Updated Aug 6, 2026
Sponsor: Aerogen Pharma Limited
Respiratory Distress Syndrome · Pre-term Infants
United States
Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep StudyActive Not Recruiting
NCT04089358Phase 3Updated Aug 6, 2026
Sponsor: Children's Oncology Group
Hematopoietic and Lymphoid Cell Neoplasm · Malignant Solid Neoplasm
United States, Canada
Assessment of CCM in HF With Higher Ejection FractionRecruiting
NCT05064709NAUpdated Aug 6, 2026
Sponsor: Impulse Dynamics
Heart Failure · Heart Failure With Preserved Ejection Fraction · Heart Failure With Mid Range Ejection Fraction · Heart Failure With Moderately Reduced Ejection Fraction
United States
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has SpreadRecruiting
NCT06324357Phase 1, Phase 2Updated Aug 6, 2026
Sponsor: Boehringer Ingelheim
Metastatic Breast Cancer · Metastatic Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma · Esophageal Adenocarcinoma
United States, Belgium, China, France, Germany +5 more
Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast CancerActive Not Recruiting
NCT02311933Phase 2Updated Aug 6, 2026
Sponsor: National Cancer Institute (NCI)
Recurrent Breast Carcinoma · Stage III Breast Cancer AJCC v7 · Stage IIIA Breast Cancer AJCC v7 · Stage IIIB Breast Cancer AJCC v7
United States
A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)Recruiting
NCT07199738N/AUpdated Aug 6, 2026
Sponsor: Smith & Nephew, Inc.
Inflammatory Arthritis · Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis) · Post-traumatic Arthritis
United States
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)Recruiting
NCT07545772Phase 2Updated Aug 6, 2026
Sponsor: Eli Lilly and Company
Irritable Bowel Syndrome · Constipation
United States, Belgium, Canada, China, Japan +3 more
Air Pollution and Development in the Boricua Youth StudyEnrolling By Invitation
NCT05368493NAUpdated Aug 6, 2026
Sponsor: New York State Psychiatric Institute
Pollution; Exposure · Neurodevelopmental Disorders
United States, Puerto Rico
Docetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast CancerCompleted
NCT01547741Phase 3Updated Aug 6, 2026
Sponsor: NSABP Foundation Inc
Breast Cancer
United States, Puerto Rico
A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After TreatmentRecruiting
NCT07293247Phase 2Updated Aug 5, 2026
Sponsor: Alliance for Clinical Trials in Oncology
Lung Non-Small Cell Carcinoma
United States
Lowering the Impact of Food Insecurity in African American Adults With Type 2 Diabetes Mellitus (LIFT-DM)Active Not Recruiting
NCT04181424NAUpdated Aug 5, 2026
Sponsor: State University of New York at Buffalo
Type 2 Diabetes
United States
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur StudyRecruiting
NCT05673148Phase 3Updated Aug 5, 2026
Sponsor: Alliance for Clinical Trials in Oncology
Metastatic Colorectal Adenocarcinoma · Stage IV Colorectal Cancer AJCC v8
United States, Canada
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric ParticipantsRecruiting
NCT05039619Phase 2Updated Aug 5, 2026
Sponsor: Hoffmann-La Roche
Lupus Nephritis
United States, Brazil, Canada, France, Italy +7 more
Zymfentra (Infliximab-dyyb) REal World Cohort STudyRecruiting
NCT07237516N/AUpdated Aug 5, 2026
Sponsor: University of North Carolina, Chapel Hill
Ulcerative Colitis (UC) · Crohn's Disease (CD) · Indeterminate Colitis · Inflammatory Bowel Disease (IBD)
United States
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionRecruiting
NCT05334069N/AUpdated Aug 5, 2026
Sponsor: Alliance for Clinical Trials in Oncology
Acute Lymphoblastic Leukemia · Acute Myeloid Leukemia · Ann Arbor Stage I Lymphoma · Ann Arbor Stage II Lymphoma
United States
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis TrialActive Not Recruiting
NCT03500328NAUpdated Aug 5, 2026
Sponsor: Johns Hopkins University
Multiple Sclerosis, Relapsing-Remitting
United States
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)Recruiting
NCT06065748Phase 3Updated Aug 5, 2026
Sponsor: Hoffmann-La Roche
Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
United States, Argentina, Australia, Austria, Belgium +32 more
Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use DisorderRecruiting
NCT07644052Phase 3Updated Aug 5, 2026
Sponsor: PleoPharma, Inc.
Cannabis Withdrawal
United States
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell LymphomaRecruiting
NCT06084936Phase 3Updated Aug 5, 2026
Sponsor: Hoffmann-La Roche
Lymphoma
United States, Australia, Brazil, Canada, China +8 more

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