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Results for “Roche”

A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to Moderate AsthmaCompleted
NCT02104674Phase 3Updated Jul 17, 2026
Sponsor: Hoffmann-La Roche
Asthma
United States, Brazil, Bulgaria, Canada, Czechia +6 more
A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative ColitisCompleted
NCT04090411Phase 2Updated Jul 17, 2026
Sponsor: Hoffmann-La Roche
Moderate to Severe Ulcerative Colitis
United States, Australia, Belgium, Bulgaria, Colombia +18 more
A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller MedicationCompleted
NCT01867125Phase 3Updated Jul 17, 2026
Sponsor: Hoffmann-La Roche
Asthma
United States, Argentina, Australia, Belgium, Canada +21 more
A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)Active Not Recruiting
NCT05296798Phase 3Updated Jul 16, 2026
Sponsor: Hoffmann-La Roche
Locally Advanced or Metastatic Breast Cancer
United States, Argentina, Belgium, Brazil, China +24 more
A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast CancerRecruiting
NCT07054190Phase 2Updated Jul 16, 2026
Sponsor: Hoffmann-La Roche
Breast Cancer
United States, Argentina, Brazil, Canada, Germany +2 more
A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)Recruiting
NCT05652686Phase 1, Phase 2Updated Jul 15, 2026
Sponsor: Phanes Therapeutics
Small Cell Lung Cancer (SCLC) · Large Cell Neuroendocrine Cancer (LCNEC) · Neuroendocrine Prostate Cancer (NEPC) · Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)
United States
A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, and Pharmacodynamics of P-CD19CD20-ALLO1 in Participants With Multiple SclerosisActive Not Recruiting
NCT07008378Phase 1Updated Jul 15, 2026
Sponsor: Genentech, Inc.
Multiple Sclerosis
United States
A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants With Advanced MASH Liver FibrosisActive Not Recruiting
NCT06903065Phase 1Updated Jul 15, 2026
Sponsor: Hoffmann-La Roche
MASH
United States, Mexico, Puerto Rico
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)Active Not Recruiting
NCT05123703Phase 3Updated Jul 15, 2026
Sponsor: Hoffmann-La Roche
Relapsing-remitting Multiple Sclerosis
United States, Argentina, Australia, Austria, Belgium +20 more
A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal JunctionActive Not Recruiting
NCT04661150Phase 2Updated Jul 15, 2026
Sponsor: Hoffmann-La Roche
Gastric Cancer · Gastroesophageal Junction Adenocarcinoma
China
A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung CancerActive Not Recruiting
NCT03456076Phase 3Updated Jul 15, 2026
Sponsor: Hoffmann-La Roche
Carcinoma, Non-Small-Cell Lung
United States, Australia, Austria, Belarus, Bosnia and Herzegovina +22 more
A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's DiseaseActive Not Recruiting
NCT03100149Phase 2Updated Jul 13, 2026
Sponsor: Hoffmann-La Roche
Parkinson's Disease
United States, Austria, France, Germany, Spain
A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted InfectionsCompleted
NCT06369220NAUpdated Jul 13, 2026
Sponsor: Hoffmann-La Roche
Chlamydia Trachomatis Infection · Neisseria Gonorrhoeae Infection · Mycoplasma Genitalium Infection
United States
A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid TumorsActive Not Recruiting
NCT06537310Phase 1Updated Jul 13, 2026
Sponsor: Hoffmann-La Roche
Cancer-Neoplasms
Australia, Belgium, Canada, Denmark, Spain
A Study of Giredestrant in Participants With Grade 1 Endometrial CancerActive Not Recruiting
NCT05634499Phase 2Updated Jul 10, 2026
Sponsor: Hoffmann-La Roche
Endometrial Cancer
United States, Canada, Italy, Poland
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) EncephalitisActive Not Recruiting
NCT05503264Phase 3Updated Jul 10, 2026
Sponsor: Hoffmann-La Roche
NMDAR Autoimmune Encephalitis · LGI1 Autoimmune Encephalitis
United States, Argentina, Brazil, China, Czechia +12 more
A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DMEActive Not Recruiting
NCT04108156Phase 3Updated Jul 10, 2026
Sponsor: Hoffmann-La Roche
Diabetic Macular Edema
United States
A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular LymphomaActive Not Recruiting
NCT04712097Phase 3Updated Jul 10, 2026
Sponsor: Hoffmann-La Roche
Relapsed or Refractory Follicular Lymphoma
United States, Australia, Brazil, China, France +10 more
An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With AlectinibActive Not Recruiting
NCT04764188N/AUpdated Jul 10, 2026
Sponsor: Hoffmann-La Roche
NSCLC
Argentina, Australia, Austria, Belgium, Bulgaria +20 more
Phase II Study of Glofitamab With Venetoclax +/- Zanubrutinib in High-risk Mantle-cell LymphomaRecruiting
NCT06558604Phase 2Updated Jul 10, 2026
Sponsor: The Lymphoma Academic Research Organisation
Lymphoma, Mantle-Cell
Belgium, France
A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)Active Not Recruiting
NCT03148418Phase 3Updated Jul 10, 2026
Sponsor: Hoffmann-La Roche
Cancer
United States, Argentina, Australia, Austria, Belgium +27 more
A Study of Risdiplam in Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular AtrophyActive Not Recruiting
NCT03779334Phase 2Updated Jul 9, 2026
Sponsor: Hoffmann-La Roche
Muscular Atrophy, Spinal
United States, Australia, Belgium, Brazil, Poland +2 more
A Study to Evaluate the Effect of RO7204239 on Insulin Sensitivity and Muscle Composition in Participants With Type 2 Diabetes Mellitus (T2DM) and Overweight or ObesityActive Not Recruiting
NCT07137585Phase 1Updated Jul 9, 2026
Sponsor: Hoffmann-La Roche
Type 2 Diabetes Mellitus · Obesity · Overweight
Germany
Combination of Atezolizumab With Dendritic Cell Vaccine in Patients With Lung CancerCompleted
NCT04487756Phase 1, Phase 2Updated Jul 8, 2026
Sponsor: Instituto Oncológico Dr Rosell
Extensive-stage Small Cell Lung Cancer
Spain
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without InhibitorsActive Not Recruiting
NCT04431726Phase 3Updated Jul 7, 2026
Sponsor: Hoffmann-La Roche
Severe Hemophilia A
United States, Australia, Austria, Belgium, Brazil +9 more

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