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Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint InhibitorRecruiting
NCT06472245Phase 3Updated Jul 23, 2026
Sponsor: OSE Immunotherapeutics
Patients With Non-Small Cell Lung Cancer
United States, Belgium, Canada, France, Germany +9 more
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative ColitisRecruiting
NCT05076175Phase 2, Phase 3Updated Jul 23, 2026
Sponsor: Bristol-Myers Squibb
Colitis, Ulcerative
United States, Australia, Belgium, Canada, France +8 more
Flap Sparing in Postoperative Radiotherapy of Oral Cavity CancersRecruiting
NCT06798922Phase 3Updated Jul 22, 2026
Sponsor: Centre Francois Baclesse
Oral Cavity Carcinoma · Flap · Radiotherapy, Adjuvant · Reconstruction Surgery
France
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUCRecruiting
NCT07720284Phase 3Updated Jul 22, 2026
Sponsor: AstraZeneca
High-risk Muscle Invasive Urothelial Carcinoma
United States, Australia, Brazil, Canada, China +11 more
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have DiabetesRecruiting
NCT07284875Phase 3Updated Jul 22, 2026
Sponsor: Kailera
Obesity · Overweight
United States, Argentina, Australia, Bulgaria, Czechia +5 more
To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCLRecruiting
NCT06072131Phase 3Updated Jul 22, 2026
Sponsor: Acrotech Biopharma Inc.
Peripheral T Cell Lymphoma
United States, Canada, Germany, Hungary, Italy +5 more
A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related ComorbiditiesRecruiting
NCT06672939Phase 3Updated Jul 22, 2026
Sponsor: Eli Lilly and Company
Obesity · Overweight
United States, Israel, Italy, Japan, Poland +1 more
Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)Recruiting
NCT07277582Phase 2, Phase 3Updated Jul 22, 2026
Sponsor: Thryv Therapeutics, Inc.
Long QT Syndrome (LQTS) 2
United States
The Efficacy and Safety of Inpegsomatropin Injection in Children With Turner Syndrome (TS) and Short StatureRecruiting
NCT07614152Phase 3Updated Jul 22, 2026
Sponsor: Xiamen Amoytop Biotech Co., Ltd.
Turner Syndrome
China
A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell TransplantationRecruiting
NCT07702578Phase 3Updated Jul 22, 2026
Sponsor: TScan Therapeutics, Inc.
AML · MDS
United States
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2Recruiting
NCT04678154Phase 3Updated Jul 22, 2026
Sponsor: Major Extremity Trauma Research Consortium
Post Operative Surgical Site Infection
United States
A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Children (6 to < 12 Years Old) With Nonsegmental VitiligoRecruiting
NCT06804811Phase 3Updated Jul 22, 2026
Sponsor: Incyte Corporation
NonSegmental Vitiligo
Argentina, Austria, Belgium, Bulgaria, Denmark +9 more
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.Recruiting
NCT06758401Phase 3Updated Jul 22, 2026
Sponsor: Pfizer
Non-Small Cell Lung Cancer · Carcinoma, Non-Small-Cell Lung · Carcinoma, Non-Small-Cell Lung (NSCLC)
United States, Argentina, Australia, Austria, Belgium +26 more
A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged ≥2 Years With Common VM, Common LM, or KTS/CLOVES SyndromeRecruiting
NCT07285005Phase 3Updated Jul 22, 2026
Sponsor: Kaken Pharmaceutical
Venous Malformations · Lymphatic Malformations · Klippel-Trenaunay Syndrome · CLOVES Syndrome
United States
PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.Recruiting
NCT06274047Phase 3Updated Jul 22, 2026
Sponsor: M.D. Anderson Cancer Center
Androgen Axis Suppression · Prostatectomy · Prostate Cancer
United States
BOTOX® vs. XEOMIN® for Chronic MigraineRecruiting
NCT05598723Phase 3Updated Jul 22, 2026
Sponsor: Naval Medical Center Camp Lejeune
Chronic Migraine
United States
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have DiabetesRecruiting
NCT07284979Phase 3Updated Jul 22, 2026
Sponsor: Kailera
Obesity
United States, Australia, Bulgaria, Poland, United Kingdom
Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous ThromboembolismRecruiting
NCT06393868Phase 3Updated Jul 22, 2026
Sponsor: Ottawa Hospital Research Institute
Venous Thromboembolism · Gastro Intestinal Bleeding · Blood Clot
Canada
A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood TransfusionsRecruiting
NCT07422480Phase 3Updated Jul 22, 2026
Sponsor: Takeda
Myelodysplastic Syndrome · Anemia
United States, Argentina, Australia, Belgium, Brazil +23 more
Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical PerformanceRecruiting
NCT06396247Phase 2, Phase 3Updated Jul 22, 2026
Sponsor: Milton S. Hershey Medical Center
Mobility Limitation
United States
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)Recruiting
NCT07428538Phase 3Updated Jul 22, 2026
Sponsor: Bausch Health Americas, Inc.
Hepatitis
United States
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal CancerRecruiting
NCT05253651Phase 3Updated Jul 22, 2026
Sponsor: Seagen, a wholly owned subsidiary of Pfizer
Colorectal Neoplasms
United States, Argentina, Australia, Austria, Belgium +20 more
Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee PainRecruiting
NCT07226258Phase 3Updated Jul 21, 2026
Sponsor: Saol Therapeutics Inc
Osteoarthritis Knee Pain
United States
Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive VentilationRecruiting
NCT07530146Phase 3Updated Jul 21, 2026
Sponsor: Helwan University
The Critically Ill Patient is Requiring Intubation · Septic Shock · Pneumonia
Egypt
A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque PsoriasisRecruiting
NCT07250802Phase 3Updated Jul 21, 2026
Sponsor: Takeda
Plaque Psoriasis
United States, China, Germany, Italy, Japan +2 more

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