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A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)Recruiting
NCT07005128Phase 3Updated Jul 16, 2026
Sponsor: Amgen
Small-cell Lung Cancer · Extensive Stage Small-cell Lung Cancer
United States, Argentina, Australia, Austria, Belgium +21 more
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell TumorsRecruiting
NCT03067181Phase 3Updated Jul 16, 2026
Sponsor: Children's Oncology Group
Childhood Extracranial Germ Cell Tumor · Extragonadal Embryonal Carcinoma · Germ Cell Tumor · Malignant Germ Cell Tumor
United States, Australia, Canada, India, Japan +4 more
Open-label Extension Study to Evaluate Metreleptin in Patients With Partial LipodystrophyRecruiting
NCT06679270Phase 3Updated Jul 16, 2026
Sponsor: Chiesi Farmaceutici S.p.A.
Familial Partial Lipodystrophy
United States
A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)Recruiting
NCT06496178Phase 3Updated Jul 16, 2026
Sponsor: Merus B.V.
Head and Neck Squamous Cell Carcinoma
United States, Argentina, Australia, Belgium, Brazil +19 more
Ketamine Treatment of Youth Suicide AttemptersRecruiting
NCT04763343Phase 3Updated Jul 16, 2026
Sponsor: Tatiana Falcone, MD
Suicide, Attempted
United States
Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Analgesia in Abdominal SurgeryRecruiting
NCT07709598Phase 2, Phase 3Updated Jul 16, 2026
Sponsor: Shanghai Huilun Pharmaceutical Co., Ltd.
Postoperative Pain
China
A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney DiseaseRecruiting
NCT05970172Phase 3Updated Jul 15, 2026
Sponsor: Astellas Pharma Global Development, Inc.
Chronic Kidney Disease · Renal Anemia
Belgium, Bulgaria, Croatia, Czechia, Denmark +17 more
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)Recruiting
NCT07453888Phase 3Updated Jul 15, 2026
Sponsor: Dompé Farmaceutici S.p.A
Non-Arteritic Anterior Ischemic Optic Neuropathy
United States
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]Recruiting
NCT06264180Phase 3Updated Jul 15, 2026
Sponsor: Replimune, Inc.
Advanced Melanoma
United States, France, Germany, Greece, Poland +2 more
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)Recruiting
NCT07482176Phase 3Updated Jul 15, 2026
Sponsor: Adverum Biotechnologies, Inc.
Neovascular Age-Related Macular Degeneration (nAMD) · Wet AMD
United States
Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain InjuryRecruiting
NCT06581003Phase 3Updated Jul 15, 2026
Sponsor: University of South Florida
Traumatic Brain Injury · Military Operations
United States
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)Recruiting
NCT05633654Phase 3Updated Jul 15, 2026
Sponsor: Gilead Sciences
Triple Negative Breast Cancer
United States, Australia, Belgium, Brazil, France +6 more
A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)Recruiting
NCT07286266Phase 3Updated Jul 15, 2026
Sponsor: GlaxoSmithKline
Ovarian Neoplasms
Australia, Canada, Japan
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and DiabetesRecruiting
NCT07284901Phase 3Updated Jul 15, 2026
Sponsor: Kailera
Obesity With Diabetes · Overweight With Diabetes
United States, Argentina, Australia, Bulgaria, Czechia +6 more
Clinical Trial With Aprotinin in the Acute Respiratory Distress Syndrome TreatmentRecruiting
NCT07317050Phase 3Updated Jul 15, 2026
Sponsor: Fundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion
Acute Respiratory Distress Syndrome (ARDS)
Spain
Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplasia (BPD)Recruiting
NCT06897839Phase 2, Phase 3Updated Jul 15, 2026
Sponsor: Airway Therapeutics, Inc.
Bronchopulmonary Dysplasia
Argentina, Belgium, France, Germany, Israel +3 more
Efficacy and Safety of Becotatug Vedotin (MRG003) Combined With Anti-PD1 as Maintenance Therapy for Recurrent and Metastatic Nasopharyngeal CarcinomaRecruiting
NCT07705243Phase 3Updated Jul 15, 2026
Sponsor: Sun Yat-sen University
Nasopharyngeal Cancinoma (NPC)
China
HRS 4642 Injection Combined With AG Versus Placebo Combined With AG Therapy in First-Line Advanced or Metastatic Pancreatic CancerRecruiting
NCT07232875Phase 3Updated Jul 15, 2026
Sponsor: Jiangsu HengRui Medicine Co., Ltd.
KRAS G12D-Mutant Advanced or Metastatic Pancreatic Cancer in the First-line Setting
China
A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants With Endometrial Cancer After Platinum-based Chemotherapy and Immunotherapy (BEHOLD-Endometrial01)Recruiting
NCT07286331Phase 3Updated Jul 15, 2026
Sponsor: GlaxoSmithKline
Neoplasms, Endometrial
Argentina, Australia, Canada, Japan, Panama
Single-Dose vs. Divided-Dose G-CSF for Stem Cell Mobilization in Healthy Allogeneic DonorsRecruiting
NCT07692841Phase 3Updated Jul 15, 2026
Sponsor: First Affiliated Hospital of Zhejiang University
Healthy Hematopoietic Stem Cell Donor · Healthy Allogeneic Hematopoietic Stem Cell Donor
China
Personalising Treatment for Myeloma Patients Based on Initial Response to NHS Treatment and Their Overall Fitness LevelRecruiting
NCT07649525Phase 3Updated Jul 15, 2026
Sponsor: University of Leeds
Multiple Myeloma (MM) · Plasma Cell Leukemia (PCL)
United Kingdom
A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Safety and Efficacy of Onradivir Tablets in Participants Aged 12 to 17 Years With Uncomplicated Influenza A.Recruiting
NCT07229547Phase 3Updated Jul 15, 2026
Sponsor: Ruijin Hospital
Influenza
China
RC148 Plus Platinum-Based Chemotherapy vs Tislelizumab Plus Platinum-Based Chemotherapy for First-Line Squamous Non-Small Cell Lung Cancer (sqNSCLC)Recruiting
NCT07416474Phase 3Updated Jul 14, 2026
Sponsor: RemeGen Co., Ltd.
Non-Small Cell Lung Cancer
China
Fixed Duration vs Continuous Anti-CD38 Antibody Therapy Among Transplant Ineligible Older Adults With Newly-Diagnosed Multiple MyelomaRecruiting
NCT06182774Phase 3Updated Jul 14, 2026
Sponsor: Canadian Cancer Trials Group
Multiple Myeloma
Canada
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 YearsRecruiting
NCT06810505Phase 3Updated Jul 14, 2026
Sponsor: AbbVie
Chronic Migraine
United States, Canada, Denmark, Hungary, Italy +6 more

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