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Immune Profiling of CLL/SLL Treated With First-Line PirtobrutinibRecruiting
NCT07428707EARLY_Phase 1Updated Aug 21, 2026
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Chronic Lymphocytic Leukemia (CLL) · Small Lymphocytic Lymphoma (SLL)
United States
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)Recruiting
NCT07058077Phase 2, Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Heterozygous Familial Hypercholesterolemia (HeFH)
United States, Australia, Belgium, Brazil, Chile +11 more
A Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS)Recruiting
NCT06433765N/AUpdated Aug 21, 2026
Sponsor: TG Therapeutics, Inc.
Multiple Sclerosis
United States
Stereotactic MR-Adaptive Radiation Therapy for Early-stage Renal CancerRecruiting
NCT07767500NAUpdated Aug 21, 2026
Sponsor: NYU Langone Health
Primary Renal Cancer
United States
Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative NeoplasmsRecruiting
NCT06303193Phase 1, Phase 2Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Myelodysplastic Syndromes
United States
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High RiskRecruiting
NCT07613294Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Atherosclerosis · Cardiovascular Diseases · Lipoprotein(a)
United States, Australia, Czechia, Hungary, Netherlands +2 more
Functional and Anatomical Visual Investigations in Patients With Early Forms of Age-related Macular DegenerationRecruiting
NCT06694272N/AUpdated Aug 21, 2026
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild
Age Related Macular Degeneration
France
A Study of LY4257496 in Participants With Cancer (OMNIRAY)Recruiting
NCT07114601Phase 1Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Breast Neoplasms · Colorectal Neoplasms · Prostate Neoplasm · Endometrial Neoplasms
United States, Canada, China, France, Germany +2 more
A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )Recruiting
NCT07101328Phase 1Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Lymphoma, Non-Hodgkin · B-cell Lymphoma · Lymphoma, Large B-Cell, Diffuse · Lymphoma, Follicular
United States, Australia, Canada, Denmark, France +7 more
Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal SepticemiaRecruiting
NCT07240077Phase 4Updated Aug 21, 2026
Sponsor: Mahidol University
Bacteremia · Streptococcus Infection
Thailand
AI Assisted Screening for VHD Using Routine Chest CT ScansRecruiting
NCT07449130N/AUpdated Aug 21, 2026
Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine
Heart Valve Diseases
China
Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell TransplantationRecruiting
NCT07573111Phase 1Updated Aug 21, 2026
Sponsor: Laguna Biotherapeutics, Inc.
Acute Leukemia · Myelodysplastic Syndrome
United States
Electromyographic Effects of Postural Correction Exercises in Individuals With Forward Head PostureRecruiting
NCT07780396NAUpdated Aug 21, 2026
Sponsor: Cairo University
Forward Head Posture
Lebanon
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideRecruiting
NCT06897475Phase 2Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Type 2 Diabetes
United States, Canada, Germany, Poland, Puerto Rico +1 more
New Robotic Knee Surgery: Does Implant Type Affect Alignment Accuracy?Recruiting
NCT07777757NAUpdated Aug 21, 2026
Sponsor: The University of Hong Kong
Knee Osteoarthristis
Hong Kong
Clinical Trial to Evaluate the Efficacy and Safety of Pulsed Electric Field Ablation Devices in the Treatment of Lung TumorsRecruiting
NCT06739031NAUpdated Aug 21, 2026
Sponsor: Energenx Medical LTD.
NSCLC
China
Amyloid PET Imaging in the Baltimore Longitudinal Study of AgingRecruiting
NCT07099053N/AUpdated Aug 21, 2026
Sponsor: National Institute on Aging (NIA)
Aging
United States
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).Recruiting
NCT05947851Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Leukemia, Lymphocytic, Chronic, B-Cell · Leukemia, Chronic Lymphocytic · Small-Cell Lymphoma · Lymphoma, Small Lymphocytic
United States, Argentina, Australia, Belgium, Brazil +13 more
GENicular Nerve Block in KNEE ArthroplastyRecruiting
NCT07589127NAUpdated Aug 21, 2026
Sponsor: Helse Møre og Romsdal HF
Osteoarthritis (OA) of the Knee · Total Knee Arthroplasty · Genicular Nerve Block
Norway
Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or AstrocytomaRecruiting
NCT06860594Phase 1Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Astrocytoma, IDH-Mutant, Grade 2 · Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant · Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant · Recurrent Astrocytoma, IDH-Mutant
United States
Lacrifill for Ocular Surface Optimization in Cataract SurgeryRecruiting
NCT07648095N/AUpdated Aug 21, 2026
Sponsor: The Eye Institute of West Florida
Cataract
United States
REFOCUS-HTN US-WEST: A Data Infrastructure to Characterize Individuals With HypertensionRecruiting
NCT07780500N/AUpdated Aug 21, 2026
Sponsor: Kaiser Permanente
Hypertension · Aldosterone Disorder · Cardiovascular Disease (CVD)
United States
A Single-arm, Multicenter Prospective Study to Evaluate the Diagnostic Performance of PROSTest in Men With PSA ≥ 3ng/ml Using Biopsy as the Sole Ground TruthRecruiting
NCT07454603N/AUpdated Aug 21, 2026
Sponsor: Wren Laboratories LLC
Prostate Cancer · Urology · Prostate Cancer (Diagnosis)
United States
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are ToleratedRecruiting
NCT07553429Phase 1, Phase 2Updated Aug 21, 2026
Sponsor: Boehringer Ingelheim
Diabetic Macular Edema
United States, Puerto Rico
Comparison of High- Versus Low-Dose Aspirin for Pregnancy Outcomes in Women at High Risk of PreeclampsiaRecruiting
NCT07779057Phase 4Updated Aug 21, 2026
Sponsor: Medicare Hospital (Pvt) Limited
Preeclampsia
Pakistan

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