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A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)Recruiting
NCT07554339Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Non-small Cell Lung Cancer
United States, Argentina, Australia, Brazil, China +9 more
Understanding Mechanisms of Normal and Disordered DefecationRecruiting
NCT03842007NAUpdated Aug 21, 2026
Sponsor: Mayo Clinic
Constipation
United States
Meningitis: Burden, Causes, Screening and Prevention in Rural Northern UgandaRecruiting
NCT05496673NAUpdated Aug 21, 2026
Sponsor: University of Rochester
Meningitis
Uganda
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)Recruiting
NCT05125302Phase 3Updated Aug 21, 2026
Sponsor: AbbVie
Migraine
United States, Puerto Rico
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or OverweightRecruiting
NCT07353931Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Osteoarthritis · Overweight or Obesity
United States, Argentina, Belgium, Brazil, Canada +9 more
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).Recruiting
NCT06751238Phase 1Updated Aug 21, 2026
Sponsor: Novartis Pharmaceuticals
Juvenile Psoriatic Arthritis
United States
Phase 3 Trial of VMX-C001 vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.Recruiting
NCT07288489Phase 3Updated Aug 21, 2026
Sponsor: VarmX B.V.
Blood Loss, Surgical · Coagulation Disorder
United States, Australia, Bulgaria, France, Japan +2 more
A Clinical Trial to Look at the Safety and Immune Responses of the RNA-based Vaccine BNT168 in Adults Living With or Without HIVRecruiting
NCT07698600Phase 1Updated Aug 21, 2026
Sponsor: BioNTech SE
HIV -1 Infection
United States
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruiting
NCT05675410Phase 3Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
United States, Canada, Puerto Rico
Digital Therapeutics for Social Cognitive Function in Schizophrenia Spectrum DisorderRecruiting
NCT07755605NAUpdated Aug 21, 2026
Sponsor: Samsung Medical Center
Schizophrenia · Schizoaffecitve Disorder
South Korea
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 DiabetesRecruiting
NCT07282600Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Overweight · Obesity
United States, Argentina, China, Czechia, Germany +9 more
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of StrokeRecruiting
NCT06615973N/AUpdated Aug 21, 2026
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Stroke · Brain Disease · Vascular Diseases · Cerebrovascular Disorder
United States
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have CirrhosisRecruiting
NCT06632457Phase 3Updated Aug 21, 2026
Sponsor: Boehringer Ingelheim
Metabolic Dysfunction Associated Steatohepatitis
United States, Argentina, Australia, Austria, Belgium +31 more
A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)Recruiting
NCT07673744Phase 2Updated Aug 21, 2026
Sponsor: TG Therapeutics, Inc.
Myasthenia Gravis
United States
Pelvic Floor Muscle Training and Dynamic Neuromuscular Stabilization Exercises in Pediatric PatientsRecruiting
NCT07267364NAUpdated Aug 21, 2026
Sponsor: Necmettin Erbakan University
Urology · Pediatric Disorder
Turkey (Türkiye)
Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical CarcinomaRecruiting
NCT06487481Phase 1Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Adrenocortical Carcinoma (ACC) · Recurrent Adrenocortical Carcinoma (ACC) · Recurrent Abdominal Adrenocortical Carcinoma (ACC) · Carcinoma, Adrenocortical
United States
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin ActionRecruiting
NCT05414409Phase 2Updated Aug 21, 2026
Sponsor: Heba M. Ismail
Type 1 Diabetes · Obesity
United States
LY4268989 in Adults With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07415044Phase 2Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Ulcerative Colitis (UC) · Ulcerative Colitis, Active Moderate · Ulcerative Colitis, Active Severe
United States, Argentina, Brazil, Canada, China +23 more
An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Primary Focal Segmental GlomerulosclerosisRecruiting
NCT06664814Phase 2Updated Aug 21, 2026
Sponsor: National Human Genome Research Institute (NHGRI)
Focal Segmental Glomerulosclerosis
United States
Effects of Probiotic Supplementation on Gut Health, Immune Response, and Well-BeingRecruiting
NCT07779265NAUpdated Aug 21, 2026
Sponsor: Orthomol Pharmazeutische Vertiebs GmbH
Gut Microbiome · Immune Responses · Well-being
Germany
Effect of Aromatherapy on the Management of Chemotherapy-Induced Neuropathy (CIN)Recruiting
NCT07779135N/AUpdated Aug 21, 2026
Sponsor: Centre Hospitalier de Colmar
Breast Cancer · Neuropathic Pain in Cancer
France
A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in IndiaRecruiting
NCT07685769Phase 4Updated Aug 21, 2026
Sponsor: Pfizer
Acute Treatment of Migraine
India
Collection of Human Biospecimens for Basic and Clinical Research Into Globin VariantsRecruiting
NCT03937817N/AUpdated Aug 21, 2026
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Alpha and Beta Thalassemia · Sickle Cell Disease · Malaria · Human Physiology
United States
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaRecruiting
NCT06885697Phase 1Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Mesothelioma · Neoplasms · Stomach Neoplasms · Pancreatic Neoplasms
United States
Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive ImpairmentRecruiting
NCT07775079NAUpdated Aug 21, 2026
Sponsor: Shifa Tameer-e-Millat University
Mild Cognitive Impairment (MCI) · Moderate Cognitive Impairment
Pakistan

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