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A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)Recruiting
NCT06312137Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Non Small Cell Lung Cancer
United States, Argentina, Australia, Austria, Belgium +26 more
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative ColitisRecruiting
NCT07071519Phase 3Updated Aug 21, 2026
Sponsor: AbbVie
Ulcerative Colitis
United States, Belgium, Brazil, Canada, China +10 more
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C MutationRecruiting
NCT06252649Phase 3Updated Aug 21, 2026
Sponsor: Amgen
Metastatic Colorectal Cancer
United States, Argentina, Australia, Austria, Belgium +30 more
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)Recruiting
NCT07058077Phase 2, Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Heterozygous Familial Hypercholesterolemia (HeFH)
United States, Australia, Belgium, Brazil, Chile +11 more
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High RiskRecruiting
NCT07613294Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Atherosclerosis · Cardiovascular Diseases · Lipoprotein(a)
United States, Australia, Czechia, Hungary, Netherlands +2 more
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).Recruiting
NCT05947851Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Leukemia, Lymphocytic, Chronic, B-Cell · Leukemia, Chronic Lymphocytic · Small-Cell Lymphoma · Lymphoma, Small Lymphocytic
United States, Argentina, Australia, Belgium, Brazil +13 more
A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)Recruiting
NCT07554339Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Non-small Cell Lung Cancer
United States, Argentina, Australia, Brazil, China +9 more
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)Recruiting
NCT05125302Phase 3Updated Aug 21, 2026
Sponsor: AbbVie
Migraine
United States, Puerto Rico
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or OverweightRecruiting
NCT07353931Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Osteoarthritis · Overweight or Obesity
United States, Argentina, Belgium, Brazil, Canada +9 more
Phase 3 Trial of VMX-C001 vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.Recruiting
NCT07288489Phase 3Updated Aug 21, 2026
Sponsor: VarmX B.V.
Blood Loss, Surgical · Coagulation Disorder
United States, Australia, Bulgaria, France, Japan +2 more
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruiting
NCT05675410Phase 3Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
United States, Canada, Puerto Rico
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 DiabetesRecruiting
NCT07282600Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Overweight · Obesity
United States, Argentina, China, Czechia, Germany +9 more
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have CirrhosisRecruiting
NCT06632457Phase 3Updated Aug 21, 2026
Sponsor: Boehringer Ingelheim
Metabolic Dysfunction Associated Steatohepatitis
United States, Argentina, Australia, Austria, Belgium +31 more
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)Recruiting
NCT05139017Phase 2, Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
DLBCL · Diffuse Large B-Cell Lymphoma
United States, Argentina, Australia, Brazil, Canada +21 more
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b StudyRecruiting
NCT06937086Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Ulcerative Colitis · Obesity or Overweight
United States, Austria, Belgium, Brazil, Bulgaria +18 more
A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic AnemiaRecruiting
NCT07086976Phase 3Updated Aug 21, 2026
Sponsor: Sanofi
Autoimmune Haemolytic Anaemia
United States, Argentina, Austria, Brazil, China +12 more
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate CancerRecruiting
NCT07213674Phase 3Updated Aug 21, 2026
Sponsor: Amgen
Metastatic Castration-resistant Prostate Cancer
United States, Australia, Austria, Belgium, Canada +13 more
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use DisorderRecruiting
NCT07219966Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Alcohol Use Disorder
United States, Belgium, China, Germany, Japan +3 more
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving HemodialysisRecruiting
NCT03969329Phase 3Updated Aug 21, 2026
Sponsor: Amgen
Secondary Hyperparathyroidism
Belgium, Czechia, France, Germany, Greece +7 more
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease StudiesRecruiting
NCT07177352Phase 3Updated Aug 21, 2026
Sponsor: Hoffmann-La Roche
Alzheimers Disease
United States, Argentina, Australia, Brazil, Canada +9 more
Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of UblituximabRecruiting
NCT05877963Phase 3Updated Aug 21, 2026
Sponsor: TG Therapeutics, Inc.
Relapsing Multiple Sclerosis
United States, Poland
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)Recruiting
NCT07513376Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Non-small Cell Lung Cancer
United States, Australia, Canada, France, Germany +11 more
A Study of TAK-360 in People With Narcolepsy or Idiopathic HypersomniaRecruiting
NCT07646678Phase 2, Phase 3Updated Aug 21, 2026
Sponsor: Takeda
Idiopathic Hypersomnia · Narcolepsy Type 1 · Narcolepsy Type 2
United States, China, Japan
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic MigraineRecruiting
NCT07018713Phase 3Updated Aug 21, 2026
Sponsor: Merz Therapeutics GmbH
Chronic Migraine
United States, Austria, Canada, Czechia, Denmark +8 more
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)Recruiting
NCT06841354Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Triple Negative Breast Neoplasms
United States, Argentina, Australia, Belgium, Brazil +29 more

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