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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideRecruiting
NCT06897475Phase 2Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Type 2 Diabetes
United States, Canada, Germany, Poland, Puerto Rico +1 more
Intervention on Mathematical Problem-Solving SkillsNot Yet Recruiting
NCT07778706NAUpdated Aug 21, 2026
Sponsor: Stanford University
Math Learning Disability · Learning Disabilities · Learning Disabilities, Child · Dyscalculia
United States
Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary MalignanciesActive Not Recruiting
NCT04068194Phase 1, Phase 2Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Locally Advanced Malignant Solid Neoplasm · Locally Advanced Unresectable Cholangiocarcinoma · Locally Advanced Unresectable Gallbladder Carcinoma · Locally Advanced Unresectable Malignant Solid Neoplasm
United States
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).Recruiting
NCT05947851Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Leukemia, Lymphocytic, Chronic, B-Cell · Leukemia, Chronic Lymphocytic · Small-Cell Lymphoma · Lymphoma, Small Lymphocytic
United States, Argentina, Australia, Belgium, Brazil +13 more
Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or AstrocytomaRecruiting
NCT06860594Phase 1Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Astrocytoma, IDH-Mutant, Grade 2 · Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-Mutant · Recurrent Adult Diffuse Midline Glioma, H3 K27-Mutant · Recurrent Astrocytoma, IDH-Mutant
United States
REFOCUS-HTN US-WEST: A Data Infrastructure to Characterize Individuals With HypertensionRecruiting
NCT07780500N/AUpdated Aug 21, 2026
Sponsor: Kaiser Permanente
Hypertension · Aldosterone Disorder · Cardiovascular Disease (CVD)
United States
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are ToleratedRecruiting
NCT07553429Phase 1, Phase 2Updated Aug 21, 2026
Sponsor: Boehringer Ingelheim
Diabetic Macular Edema
United States, Puerto Rico
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung CancerActive Not Recruiting
NCT06632327Phase 3Updated Aug 21, 2026
Sponsor: Alliance for Clinical Trials in Oncology
Resectable Lung Non-Small Cell Carcinoma · Stage II Lung Cancer AJCC v8 · Stage IIIA Lung Cancer AJCC v8 · Stage IIIB Lung Cancer AJCC v8
United States
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)Recruiting
NCT05125302Phase 3Updated Aug 21, 2026
Sponsor: AbbVie
Migraine
United States, Puerto Rico
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or OverweightRecruiting
NCT07353931Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Osteoarthritis · Overweight or Obesity
United States, Argentina, Belgium, Brazil, Canada +9 more
Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin LymphomaActive Not Recruiting
NCT03884998Phase 1Updated Aug 21, 2026
Sponsor: City of Hope Medical Center
Chronic Lymphocytic Leukemia · Diffuse Large B-Cell Lymphoma · Follicular Lymphoma · Indolent Non-Hodgkin Lymphoma
United States
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).Recruiting
NCT06751238Phase 1Updated Aug 21, 2026
Sponsor: Novartis Pharmaceuticals
Juvenile Psoriatic Arthritis
United States
Phase 3 Trial of VMX-C001 vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.Recruiting
NCT07288489Phase 3Updated Aug 21, 2026
Sponsor: VarmX B.V.
Blood Loss, Surgical · Coagulation Disorder
United States, Australia, Bulgaria, France, Japan +2 more
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruiting
NCT05675410Phase 3Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
United States, Canada, Puerto Rico
A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose AdministrationNot Yet Recruiting
NCT07780383Phase 1Updated Aug 21, 2026
Sponsor: Bristol-Myers Squibb
Alzheimer's Disease · Healthy Participants
United States
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 DiabetesRecruiting
NCT07282600Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Overweight · Obesity
United States, Argentina, China, Czechia, Germany +9 more
A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic DermatitisActive Not Recruiting
NCT06136741Phase 2Updated Aug 21, 2026
Sponsor: Nektar Therapeutics
Moderate to Severe Atopic Dermatitis
United States, Australia, Bulgaria, Canada, Croatia +5 more
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have CirrhosisRecruiting
NCT06632457Phase 3Updated Aug 21, 2026
Sponsor: Boehringer Ingelheim
Metabolic Dysfunction Associated Steatohepatitis
United States, Argentina, Australia, Austria, Belgium +31 more
Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment TrialActive Not Recruiting
NCT05554367Phase 2Updated Aug 21, 2026
Sponsor: National Cancer Institute (NCI)
Exocrine Pancreas Carcinoma · Malignant Solid Neoplasm · Ovarian Low Grade Serous Adenocarcinoma · Stage IV Ovarian Cancer AJCC v8
United States, Puerto Rico
LY4268989 in Adults With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07415044Phase 2Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Ulcerative Colitis (UC) · Ulcerative Colitis, Active Moderate · Ulcerative Colitis, Active Severe
United States, Argentina, Brazil, Canada, China +23 more
Evaluation of Delefilcon A Contact LensesCompleted
NCT06884202NAUpdated Aug 21, 2026
Sponsor: Alcon Research
Refractive Errors · Myopia
United States
A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or PancreasActive Not Recruiting
NCT06882746Phase 1Updated Aug 21, 2026
Sponsor: Boehringer Ingelheim
Colorectal Carcinoma · Gastric Carcinoma · Pancreatic Ductal Adenocarcinoma
United States, Germany, Spain
Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)Recruiting
NCT07297979Phase 1Updated Aug 21, 2026
Sponsor: Amgen
Ewing Sarcoma
United States, Australia
Attachment Inhibitor Comparison in Heavily Treatment Experienced PatientsActive Not Recruiting
NCT02362503Phase 3Updated Aug 21, 2026
Sponsor: ViiV Healthcare
HIV Infections
United States, Argentina, Australia, Belgium, Brazil +20 more
Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.Active Not Recruiting
NCT03150329Phase 1Updated Aug 21, 2026
Sponsor: City of Hope Medical Center
Grade 3b Follicular Lymphoma · Recurrent B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between DLBCL and Classic HL · Recurrent Classic Hodgkin Lymphoma · Recurrent Diffuse Large B-Cell Lymphoma
United States

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