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A Phase 2/3 Study of Brepocitinib in Adults With Cutaneous SarcoidosisRecruiting
NCT06978725Phase 2, Phase 3Updated Aug 21, 2026
Sponsor: Priovant Therapeutics, Inc.
Cutaneous Sarcoidosis
United States
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)Recruiting
NCT06077760Phase 3Updated Aug 21, 2026
Sponsor: Merck Sharp & Dohme LLC
Non-small Cell Lung Cancer
United States, Argentina, Australia, Belgium, Brazil +28 more
Study to Evaluate the Efficacy and Safety of BMN 333 Versus Vosoritide in Children With AchondroplasiaRecruiting
NCT07441876Phase 2, Phase 3Updated Aug 21, 2026
Sponsor: BioMarin Pharmaceutical
Achondroplasia
United States, Australia, Canada, Italy, Japan +4 more
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood SugarRecruiting
NCT07754461Phase 3Updated Aug 21, 2026
Sponsor: Boehringer Ingelheim
Type 2 Diabetes
United States, Australia, Canada, India, New Zealand +1 more
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly IncretinRecruiting
NCT07392190Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Overweight · Obesity
United States, Australia, Belgium, Brazil, China +9 more
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)Recruiting
NCT07174336Phase 3Updated Aug 21, 2026
Sponsor: Eli Lilly and Company
Breast Neoplasms · Neoplasm Metastasis
United States, Argentina, Australia, Belgium, Brazil +14 more
A Study to Evaluate the Efficacy and Safety of Subcutaneous Nomlabofusp in Subjects With Friedreich's AtaxiaRecruiting
NCT07778836Phase 3Updated Aug 21, 2026
Sponsor: Larimar Therapeutics, Inc.
Friedreich Ataxia · Friedreich's Ataxia
United States
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung CancerRecruiting
NCT07365241Phase 3Updated Aug 21, 2026
Sponsor: AbbVie
Small Cell Lung Cancer
United States, Austria, Germany, Greece, Japan +2 more
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AMLRecruiting
NCT07007312Phase 3Updated Aug 20, 2026
Sponsor: Kura Oncology, Inc.
Acute Myeloid Leukemia (AML)
United States, Australia, Belgium, Canada, Czechia +11 more
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07184996Phase 3Updated Aug 20, 2026
Sponsor: Sanofi
Ulcerative Colitis
United States, Bulgaria, Canada, China, Czechia +15 more
A Study to Test Whether Nerandomilast Helps People With Systemic SclerosisRecruiting
NCT07497087Phase 3Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Systemic Sclerosis
United States, Argentina, Australia, Austria, Belgium +40 more
Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation RetinopathyRecruiting
NCT05844982Phase 3Updated Aug 20, 2026
Sponsor: Jaeb Center for Health Research
Radiation Retinopathy · Visual Impairment
United States
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and ProteinuriaRecruiting
NCT05457283Phase 3Updated Aug 20, 2026
Sponsor: Bayer
Chronic Kidney Disease · Proteinuria · Children
United States, Argentina, Australia, Austria, Belgium +27 more
Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary DiseaseRecruiting
NCT05844462Phase 3Updated Aug 20, 2026
Sponsor: Assistance Publique - Hôpitaux de Paris
Pulmonary Hypertension · Chronic Obstructive Pulmonary Disease
France
Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe TraumaRecruiting
NCT03368092Phase 3Updated Aug 20, 2026
Sponsor: University Hospital, Strasbourg, France
Multiple Trauma · Respiratory Distress Syndrome, Adult
France
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2Recruiting
NCT07227246Phase 3Updated Aug 20, 2026
Sponsor: Joseph Broderick, MD
Intracerebral Hemorrhage
United States, Canada, Germany, Japan, Spain +1 more
A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLLRecruiting
NCT05197192Phase 3Updated Aug 20, 2026
Sponsor: German CLL Study Group
Chronic Lymphocytic Leukemia
Germany
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)Recruiting
NCT06103864Phase 3Updated Aug 20, 2026
Sponsor: AstraZeneca
Breast Cancer
United States, Argentina, Australia, Brazil, Canada +19 more
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic EsophagitisRecruiting
NCT07112378Phase 3Updated Aug 20, 2026
Sponsor: Regeneron Pharmaceuticals
Eosinophilic Esophagitis (EoE)
United States
REGN7508 in Adult Participants for Prevention of Cancer-Associated ThrombosisRecruiting
NCT07410117Phase 3Updated Aug 20, 2026
Sponsor: Regeneron Pharmaceuticals
Cancer-Associated Thrombosis (CAT)
United States, Georgia, Japan
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular DiseaseRecruiting
NCT07064473Phase 3Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Diabetes Mellitus, Type 2 · Hypertension · Cardiovascular Diseases
United States, Argentina, Australia, Austria, Belgium +46 more
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus ErythematosusRecruiting
NCT07430306Phase 3Updated Aug 20, 2026
Sponsor: AstraZeneca
Systemic Lupus Erythematosus
United States, Canada, France, Germany, Italy +4 more
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)Recruiting
NCT07107945Phase 3Updated Aug 20, 2026
Sponsor: Boehringer Ingelheim
Chronic Kidney Disease
United States, Argentina, Australia, Belgium, Canada +13 more
Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDRRecruiting
NCT06790784Phase 3Updated Aug 20, 2026
Sponsor: Jaeb Center for Health Research
Proliferative Diabetic Retinopathy (PDR)
United States
Effects of Stopping Hydroxychloroquine in Elderly Lupus DiseaseRecruiting
NCT05799378Phase 3Updated Aug 20, 2026
Sponsor: NYU Langone Health
Systemic Lupus Erythematosus
United States

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