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Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)Recruiting
NCT03486873Phase 3Updated Aug 18, 2026
Sponsor: Merck Sharp & Dohme LLC
Solid Tumors · Hematologic Malignancies
United States, Argentina, Australia, Austria, Belgium +46 more
NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver DiseaseRecruiting
NCT06453915EARLY_Phase 1Updated Aug 18, 2026
Sponsor: University of California, Davis
Positron Emission Tomography
United States
Tissue Procurement for Biomedical ResearchRecruiting
NCT00182858N/AUpdated Aug 18, 2026
Sponsor: National Institute on Aging (NIA)
Normal Volunteers
United States
Integrated Oral Care Intervention for Xerostomia in Diabetes PatientsRecruiting
NCT07425275NAUpdated Aug 18, 2026
Sponsor: Khyber Medical University Peshawar
Diabetes Mellitus · Diabetic Neuropathies
Pakistan
PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)Recruiting
NCT06920628Phase 1Updated Aug 18, 2026
Sponsor: National Institute of Mental Health (NIMH)
Long COVID · Post Acute Sequelae of COVID-19
United States
Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomasRecruiting
NCT03258567Phase 2Updated Aug 18, 2026
Sponsor: National Cancer Institute (NCI)
Epstein-Barr Virus Infections · Lymphoma · Lymphoproliferative Disorder · Disorders, Lymphoproliferative
United States
Use of Cysteamine in the Treatment of CystinosisRecruiting
NCT00359684N/AUpdated Aug 18, 2026
Sponsor: National Human Genome Research Institute (NHGRI)
Cystinosis
United States
Healing Hearts of Hospitalized PatientsRecruiting
NCT06935604NAUpdated Aug 18, 2026
Sponsor: Stanford University
Well-Being, Psychological · Anxiety · Affect · Relaxation
United States
A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV RemissionRecruiting
NCT05719441Phase 2Updated Aug 18, 2026
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Acute HIV Infection
United States, Brazil, Peru
Can a Pain Monitor Predict When Postoperative Intensive Care Unit Patients Are Ready to Breathe on Their Own? A Pilot StudyRecruiting
NCT07771101N/AUpdated Aug 18, 2026
Sponsor: Seoul National University Hospital
Ventilator Weaning · Airway Extubation · Respiration, Artificial
South Korea
Speech Motor Learning and Retention (Master Protocol)Recruiting
NCT06467292NAUpdated Aug 18, 2026
Sponsor: Yale University
Speech
United States
Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With LipodystrophyRecruiting
NCT05419037N/AUpdated Aug 18, 2026
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Lipodystrophy
United States
Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07686081Phase 3Updated Aug 18, 2026
Sponsor: Vanda Pharmaceuticals
Ulcerative Colitis (UC)
United States
Monitoring the Effect of Mental Fatigue on Physical Performance Using Wearable Sensors and Physiological ParametersRecruiting
NCT07323810NAUpdated Aug 18, 2026
Sponsor: Vrije Universiteit Brussel
Mental Fatigue
Belgium
Investigating the Combination of Bexmarilimab and Nivolumab in Solid Tumours, Melanoma and NSCLCRecruiting
NCT07718243Phase 1, Phase 2Updated Aug 18, 2026
Sponsor: Institute of Cancer Research, United Kingdom
Melanoma (Skin Cancer) · Non Small Cell Lung Cancer · Solid Tumor in Advanced Stage
United Kingdom
MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in ChildrenRecruiting
NCT05541276Phase 3Updated Aug 18, 2026
Sponsor: Arash Afshari
Emergence Delirium
Denmark
A Study of the Intestinal Microbiota in Children and Adolescents With Eating Disorders. A Perspective From PsychoneuroimmunologyRecruiting
NCT07066033N/AUpdated Aug 18, 2026
Sponsor: Esther Nova
Eating Disorders in Adolescence · Eating Disorders in Children
Spain
Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant MelanomaRecruiting
NCT04598009Phase 2Updated Aug 18, 2026
Sponsor: University of California, San Francisco
Melanoma Stage III · Melanoma Stage IV
United States
Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)Recruiting
NCT07322133Phase 4Updated Aug 18, 2026
Sponsor: University of California, Davis
Hypotension and Shock · Pulmonary Hypertension of the Newborn (PPHN) · Hypoxemic Respiratory Failure
United States
Safety and Efficacy Study of Sorbitol With Neoadjuvant Chemotherapy Combined With Tirellizumab (PD-1 Inhibitor) in Patients With Locally Advanced Gastric CancerRecruiting
NCT06826079Phase 2Updated Aug 18, 2026
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Gastric Junction Adenocarcinoma · Gastric Cancer · Immunotherapy · Neoadjuvant Therapies
China
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary FibrosisRecruiting
NCT07201922Phase 3Updated Aug 18, 2026
Sponsor: Boehringer Ingelheim
Familial Pulmonary Fibrosis · Interstitial Lung Abnormalities · Interstitial Lung Diseases
United States, Argentina, Australia, Belgium, Canada +8 more
Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma in Patients With Extramedullary DiseaseRecruiting
NCT06627751Phase 2Updated Aug 18, 2026
Sponsor: Roswell Park Cancer Institute
Extramedullary Disease in Multiple Myeloma · Recurrent Multiple Myeloma · Refractory Multiple Myeloma
United States
Morphological Characteristics of Mandibular Molar Furcation Involvement and Efficacy of Regenerative Surgical TreatmentRecruiting
NCT07770256NAUpdated Aug 18, 2026
Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City
Periodontitis · Periodontitis (Stage 3) · Furcation Defects
Vietnam
A Phase 1a/1b, First-Time-in-Human Study of CT-202, a Nectin-4 Directed Bispecific Antibody, in Participants With Recurring Triple Negative Breast, Colorectal, Urothelial CancersRecruiting
NCT07545122Phase 1Updated Aug 18, 2026
Sponsor: Context Therapeutics Inc.
Triple Negative Breast Cancer (TNBC) · Colorectal Cancer · Urothelial Cancer
Australia
French Assessment of MRD by Liquid Biopsies in Stage III CRC Patients (FRENCH.MRD.CRC)Recruiting
NCT06287814N/AUpdated Aug 18, 2026
Sponsor: University Hospital, Montpellier
Colorectal Cancer · Stage III Colon Cancer · Minimal Residual Disease · Liquid Biopsy
France

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