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A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)Recruiting
NCT07366034Phase 3Updated Aug 18, 2026
Sponsor: Boehringer Ingelheim
Fibrosing Interstitial Lung Disease
United States, Argentina, Australia, Belgium, Brazil +17 more
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07185009Phase 3Updated Aug 18, 2026
Sponsor: Sanofi
Ulcerative Colitis
United States, Canada, Georgia, Japan, Lithuania +3 more
A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)Recruiting
NCT06858579Phase 3Updated Aug 18, 2026
Sponsor: Dianthus Therapeutics
Chronic Inflammatory Demyelinating Polyneuropathy
United States, Argentina, Australia, Belgium, Brazil +24 more
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and ObesityRecruiting
NCT07567001Phase 3Updated Aug 18, 2026
Sponsor: Novo Nordisk A/S
Obesity · Heart Failure
United States, Argentina, Australia, Brazil, Bulgaria +22 more
Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom BurdenRecruiting
NCT07621809Phase 3Updated Aug 18, 2026
Sponsor: Novartis Pharmaceuticals
Sjögren´s Disease
United States, Australia, Canada
A Study of Olezarsen for the Treatment of Familial Chylomicronemia Syndrome (FCS) in Pediatric ParticipantsRecruiting
NCT07727538Phase 3Updated Aug 18, 2026
Sponsor: Ionis Pharmaceuticals, Inc.
Familial Chylomicronemia Syndrome
United States
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress DisorderRecruiting
NCT07570654Phase 2, Phase 3Updated Aug 18, 2026
Sponsor: COMPASS Pathways
PTSD - Post Traumatic Stress Disorder · PTSD · PTSD Symptoms · PTSD, Post Traumatic Stress Disorder
United States
Adjuvant Concurrent Chemoradiotherapy Versus Radiotherapy in Early-stage Cervical Cancer PatientsRecruiting
NCT05277688Phase 3Updated Aug 18, 2026
Sponsor: Ruijin Hospital
Cervical Cancer
China
IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)Recruiting
NCT07104032Phase 3Updated Aug 18, 2026
Sponsor: Ono Pharmaceutical Co., Ltd.
Relapsed/Refractory Primary Central Nervous System Lymphoma
United States, Australia, Czechia, France, Italy +1 more
Allopurinol in DepressionRecruiting
NCT07574060Phase 2, Phase 3Updated Aug 18, 2026
Sponsor: Tanta University
Depression
Egypt
A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)Recruiting
NCT07393282Phase 3Updated Aug 18, 2026
Sponsor: Regeneron Pharmaceuticals
High Risk Smoldering Multiple Myeloma (HR-SMM)
United States
SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous MelanomaRecruiting
NCT06743126Phase 3Updated Aug 18, 2026
Sponsor: Immatics US, Inc.
Melanoma, Cutaneous Malignant
United States, Canada, France, Germany, Netherlands +1 more
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple SclerosisRecruiting
NCT07299019Phase 3Updated Aug 18, 2026
Sponsor: Zenas BioPharma (USA), LLC
Secondary Progressive Multiple Sclerosis
United States, Croatia, Czechia, Lithuania, Poland +1 more
Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.Recruiting
NCT05948943Phase 2, Phase 3Updated Aug 18, 2026
Sponsor: Novartis Pharmaceuticals
Lymphatic Malformations
United States, Argentina, Australia, Belgium, Czechia +7 more
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic AdenocarcinomaRecruiting
NCT07491445Phase 3Updated Aug 18, 2026
Sponsor: Revolution Medicines, Inc.
Pancreatic Cancer · Pancreatic Cancer Metastatic · PDAC · PDAC - Pancreatic Ductal Adenocarcinoma
United States, Australia, Japan
A Study of BEBT-209 Plus Chemotherapy in Patients With Locally Advanced or Metastatic Triple-Negative Breast CancerRecruiting
NCT07544056Phase 2, Phase 3Updated Aug 18, 2026
Sponsor: BeBetter Med Inc
Locally Advanced Triple-negative Breast Cancer · Metastatic Triple-negative Breast Cancer
China
Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1Recruiting
NCT07486934Phase 3Updated Aug 18, 2026
Sponsor: Dyne Therapeutics
Myotonic Dystrophy Type 1 (DM1) · DM1 · Myotonic Dystrophy · Steinert Disease
United States, Belgium, Denmark, France, Germany +5 more
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)Recruiting
NCT03486873Phase 3Updated Aug 18, 2026
Sponsor: Merck Sharp & Dohme LLC
Solid Tumors · Hematologic Malignancies
United States, Argentina, Australia, Austria, Belgium +46 more
Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07686081Phase 3Updated Aug 18, 2026
Sponsor: Vanda Pharmaceuticals
Ulcerative Colitis (UC)
United States
MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in ChildrenRecruiting
NCT05541276Phase 3Updated Aug 18, 2026
Sponsor: Arash Afshari
Emergence Delirium
Denmark
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary FibrosisRecruiting
NCT07201922Phase 3Updated Aug 18, 2026
Sponsor: Boehringer Ingelheim
Familial Pulmonary Fibrosis · Interstitial Lung Abnormalities · Interstitial Lung Diseases
United States, Argentina, Australia, Belgium, Canada +8 more
A Study of Orelabrutinib in Patients With Primary Progressive Multiple SclerosisRecruiting
NCT07067463Phase 3Updated Aug 18, 2026
Sponsor: Zenas BioPharma (USA), LLC
Multiple Sclerosis (MS) Primary Progressive
United States, Bulgaria, Croatia, Czechia, Estonia +8 more
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP TrialRecruiting
NCT05863195Phase 3Updated Aug 18, 2026
Sponsor: ECOG-ACRIN Cancer Research Group
Metastatic Colorectal Carcinoma · Metastatic Malignant Neoplasm in the Liver · Stage IV Colorectal Cancer AJCC v8 · Unresectable Colorectal Carcinoma
United States
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER StudyRecruiting
NCT07097142Phase 3Updated Aug 18, 2026
Sponsor: NRG Oncology
Muscle Invasive Bladder Urothelial Carcinoma · Stage II Bladder Cancer AJCC v8 · Stage IIIA Bladder Cancer AJCC v8
United States
Vitamin D and Type 2 Diabetes - Treat-To-TargetRecruiting
NCT07448974Phase 3Updated Aug 18, 2026
Sponsor: Tufts Medical Center
Prediabetes · Type 2 Diabetes (T2DM)
United States

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