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Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)Recruiting
NCT06126276Phase 2Updated Aug 18, 2026
Sponsor: National Cancer Institute (NCI)
Malignant Female Reproductive System Neoplasm · Malignant Solid Neoplasm · Recurrent Malignant Female Reproductive System Neoplasm · Recurrent Malignant Solid Neoplasm
United States, Puerto Rico
Study of Inherited Neurological DisordersRecruiting
NCT00004568N/AUpdated Aug 18, 2026
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Motor Neuron Disease · Muscular Disease · Muscular Dystrophy · Peripheral Nervous System Disease
United States, Mali
A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa ColonizationRecruiting
NCT07088926Phase 2Updated Aug 18, 2026
Sponsor: AstraZeneca
Bronchiectasis With Pseudomonas Aeruginosa Colonization
United States, Argentina, Australia, Belgium, Brazil +20 more
Behavioral Safety and Fentanyl Education: BSAFERecruiting
NCT07219082NAUpdated Aug 18, 2026
Sponsor: San Francisco Department of Public Health
Drug Overdose · Drug Overdose Accidental
United States
Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier RegistryRecruiting
NCT02302742N/AUpdated Aug 18, 2026
Sponsor: University of Kansas Medical Center
Breast Cancer · Hereditary Breast and Ovarian Cancer
United States
Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM TrialRecruiting
NCT07605416Phase 2Updated Aug 18, 2026
Sponsor: National Cancer Institute (NCI)
Plasma Cell Leukemia
United States
[212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck CancersRecruiting
NCT06479811Phase 1Updated Aug 18, 2026
Sponsor: National Cancer Institute (NCI)
Sinonasal Neuroendocrine Carcinoma · Nasopharyngeal Carcinoma · Esthesioneuroblastoma · Olfactory Neuroblastoma
United States
Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation SyndromeRecruiting
NCT07722247N/AUpdated Aug 18, 2026
Sponsor: Kata Culina
Pseudoexfoliation Syndrome · Cataract · Astigmatism
Croatia
A Multicenter Prospective Observational Cohort Study for Digestive Tract Tumor Screening Using Multi-Target Blood and Fecal BiomarkersRecruiting
NCT07769892N/AUpdated Aug 18, 2026
Sponsor: Xijing Hospital
Gastrointestinal Cancers
China
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)Recruiting
NCT06292780Phase 1, Phase 2Updated Aug 18, 2026
Sponsor: Regeneron Pharmaceuticals
Relapsed/Refractory Systemic Light Chain Amyloidosis
United States, Greece, South Korea, Spain, Taiwan +1 more
Core Endurance Versus Segmental Stabilization Exercise in Recreational Athletes With Low Back PainRecruiting
NCT07760103NAUpdated Aug 18, 2026
Sponsor: Uskudar University
Low Back Pain · Athletic Injuries
Turkey (Türkiye)
Natural History of Individuals With Immune System Problems That Lead to Fungal InfectionsRecruiting
NCT01386437N/AUpdated Aug 18, 2026
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Chronic Mucocutaneous Candidiasis · Invasive Aspergillosis · CARD9 · APECED
United States
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With ObesityRecruiting
NCT07218445Phase 4Updated Aug 18, 2026
Sponsor: Mayo Clinic
Obesity · Menopause Hot Flashes
United States
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body WeightRecruiting
NCT07770841Phase 3Updated Aug 18, 2026
Sponsor: Novo Nordisk A/S
Overweight · Obesity
United States, Belgium, Bulgaria, Denmark, France +5 more
Routine Antiemetic Prophylaxis for Nonfasted Parturients Undergoing Cesarean Sections Under Spinal AnesthesiaRecruiting
NCT07740577Phase 4Updated Aug 18, 2026
Sponsor: Sanliurfa Education and Research Hospital
Intraoperative Nausea-retching-vomiting Episodes · Spinal Aneshtesia · Ceserean Section · Antiemetic Therapy
Turkey (Türkiye)
A Phase I Clinical Trial to Evaluate HECN30227 Injection in Healthy Subjects and Subjects With Chronic Hepatitis BRecruiting
NCT07771140Phase 1Updated Aug 18, 2026
Sponsor: Sunshine Lake Pharma Co., Ltd.
HBV Infection
China
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)Recruiting
NCT07366034Phase 3Updated Aug 18, 2026
Sponsor: Boehringer Ingelheim
Fibrosing Interstitial Lung Disease
United States, Argentina, Australia, Belgium, Brazil +17 more
Evaluating The Role Of Montelukast In Management Of Acute BronchiolitisRecruiting
NCT07770464Phase 2Updated Aug 18, 2026
Sponsor: Pakistan Institute of Medical Sciences
Acute Bronchiolitis
Pakistan
Capecitabine in ER+/HER2-negative Breast CancerRecruiting
NCT07631052Phase 2Updated Aug 18, 2026
Sponsor: University Health Network, Toronto
ER-positive, HER2-negative Breast Cancer · Breast Cancer Stage I · Breast Cancer Stage II · Breast Cancer Stage III
Canada
Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)Recruiting
NCT07241585NAUpdated Aug 18, 2026
Sponsor: Case Comprehensive Cancer Center
Nonmelanoma Skin Cancer · Basal Cell Carcinoma · Squamous Cell Carcinoma
United States
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell CarcinomasRecruiting
NCT07217171Phase 1Updated Aug 18, 2026
Sponsor: EvolveImmune United, Inc
Bladder Cancer · Squamous Cell Carcinoma of the Lung · Esophageal Squamous Cell Carcinoma · Tongue Squamous Cell Carcinoma
United States
Safety Registry of a Fecal Microbiota Transplant CohortRecruiting
NCT06311006N/AUpdated Aug 18, 2026
Sponsor: Assistance Publique - Hôpitaux de Paris
Clostridium Difficile Infections
France
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative ColitisRecruiting
NCT07185009Phase 3Updated Aug 18, 2026
Sponsor: Sanofi
Ulcerative Colitis
United States, Canada, Georgia, Japan, Lithuania +3 more
Diagnosis and Treatment of Patients With Inborn Errors of MetabolismRecruiting
NCT00369421N/AUpdated Aug 18, 2026
Sponsor: National Human Genome Research Institute (NHGRI)
Arterial Calcification Due to Deficiency of CD73
United States
Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin ResistanceRecruiting
NCT05470504Phase 2Updated Aug 18, 2026
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Insulin Receptor Mutation · Partial Lipodystrophy
United States

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