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A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistaminesRecruiting
NCT06868212Phase 3Updated Aug 19, 2026
Sponsor: Novartis Pharmaceuticals
Chronic Spontaneous Urticaria (CSU)
United States
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)Recruiting
NCT06452277Phase 3Updated Aug 19, 2026
Sponsor: Bayer
Advanced Non-small Cell Lung Cancer, HER2 Mutation
United States, Argentina, Australia, Austria, Belgium +31 more
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney DiseaseRecruiting
NCT07355296Phase 2Updated Aug 19, 2026
Sponsor: Boehringer Ingelheim
Proteinuric Kidney Diseases
United States, Argentina, Australia, Belgium, Brazil +28 more
En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope DeviceRecruiting
NCT04235764N/AUpdated Aug 19, 2026
Sponsor: National Cancer Institute (NCI)
Bladder Cancer
United States
Ketone Ester And Salt (KEAS) in Older AdultsRecruiting
NCT06868719NAUpdated Aug 19, 2026
Sponsor: Indiana University
Salt; Excess · Hypertension · Aging · Inflammation
United States
Brain Organization, Development, and Response to Intervention in Individual NeonatesRecruiting
NCT05843396NAUpdated Aug 19, 2026
Sponsor: Washington University School of Medicine
Development, Infant
United States
Study of the Brain's Natural Cleaning System in Potential Organ Donors.Recruiting
NCT07682155NAUpdated Aug 19, 2026
Sponsor: Germans Trias i Pujol Hospital
Anatomical Description
Spain
Neuroimmune Responses to Exercise in Chronic Back PainRecruiting
NCT07497425NAUpdated Aug 19, 2026
Sponsor: McGill University
Chronic Low Back Pain (CLBP)
Canada
Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic PainRecruiting
NCT05868668NAUpdated Aug 19, 2026
Sponsor: The Cleveland Clinic
Erectile Dysfunction Due to Arterial Insufficiency · Erectile Dysfunction · Erectile Dysfunction Due to Arterial Disease · Chronic Pelvic Pain Syndrome
United States
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney DiseaseRecruiting
NCT07235059Phase 1Updated Aug 19, 2026
Sponsor: Novartis Pharmaceuticals
Chronic Kidney Disease
United States, Germany
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain MetsRecruiting
NCT05317858Phase 3Updated Aug 19, 2026
Sponsor: InSightec
Brain Tumor · Non Small Cell Lung Cancer
United States, Canada, South Korea
Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid TumorsRecruiting
NCT05733949EARLY_Phase 1Updated Aug 19, 2026
Sponsor: City of Hope Medical Center
Metastatic Malignant Solid Neoplasm
United States
Evaluation of a Disability-Focused Sexual and Reproductive Health Curriculum for Health Students in TanzaniaRecruiting
NCT07772778Phase 3Updated Aug 19, 2026
Sponsor: University of Minnesota
Sexual and Reproductive Health · Disability · Health Knowledge, Attitudes, Practice · Health Education
Tanzania
An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)Recruiting
NCT06996652Phase 2Updated Aug 19, 2026
Sponsor: Yale University
REM Sleep Behavior Disorder
United States, Canada
Smoking Cessation Counseling Performance Among Medical InternsRecruiting
NCT07650721NAUpdated Aug 19, 2026
Sponsor: Assiut University
Smoking Cessation
Egypt
Ketone Ester and Salt (KEAS) in Young AdultsRecruiting
NCT05545501NAUpdated Aug 19, 2026
Sponsor: Indiana University
Salt; Excess · Hypertension
United States
Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTFRecruiting
NCT03604315Phase 1Updated Aug 19, 2026
Sponsor: M.D. Anderson Cancer Center
Breast Carcinoma · Fallopian Tube Carcinoma · Ovarian Carcinoma · Primary Peritoneal Carcinoma
United States
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)Recruiting
NCT06898099NAUpdated Aug 19, 2026
Sponsor: Rennes University Hospital
Chronic Insomnia
France
Non-Invasive Neuromodulation for Essential Tremor: Long-Term Safety and Effectiveness StudyRecruiting
NCT07774598NAUpdated Aug 19, 2026
Sponsor: Ruijin Hospital
Essential Tremor
China
Monitoring of Immunological Mechanisms and Biomarkers Underlying Efficacy of Immunotherapy in Patients With Early Stage CancerRecruiting
NCT07427186NAUpdated Aug 19, 2026
Sponsor: Institut Claudius Regaud
Solid Cancers
France
Accuracy of Corneal Astigmatism in Different Region ModesRecruiting
NCT03299530N/AUpdated Aug 19, 2026
Sponsor: Wenzhou Medical University
Astigmatism · Cornea
China
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2Recruiting
NCT07288398Phase 3Updated Aug 19, 2026
Sponsor: Tenax Therapeutics, Inc.
Pulmonary Hypertension Associated With HFpEF
United States, Argentina, Austria, Brazil, Bulgaria +10 more
Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSeaseRecruiting
NCT06430684EARLY_Phase 1Updated Aug 19, 2026
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
Chronic Kidney Diseases · Pediatric Kidney Disease
United States
Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast CancersRecruiting
NCT05919108Phase 2Updated Aug 19, 2026
Sponsor: Vanderbilt-Ingram Cancer Center
Anatomic Stage I Breast Cancer · Anatomic Stage II Breast Cancer · Anatomic Stage III Breast Cancer · Invasive Breast Lobular Carcinoma
United States
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued TreatmentRecruiting
NCT07444567Phase 3Updated Aug 19, 2026
Sponsor: AstraZeneca
Asthma · Eosinophilic Granulomatosis With Polyangiitis (EGPA) · Hypereosinophilic Syndrome (HES)
United States, Argentina, Austria, Belgium, Canada +9 more

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