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Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)Active Not Recruiting
NCT04411654Phase 1, Phase 2Updated Aug 19, 2026
Sponsor: Prevail Therapeutics
Gaucher Disease, Type 2
United States, United Kingdom
Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV RemissionRecruiting
NCT02140255Phase 1, Phase 2Updated Aug 19, 2026
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infection
United States, Argentina, Brazil, Haiti, Kenya +8 more
A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma PatientsRecruiting
NCT06549595Phase 3Updated Aug 19, 2026
Sponsor: AstraZeneca
Untreated Follicular Lymphoma
United States, Australia, Belgium, Brazil, Canada +18 more
Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility StudyRecruiting
NCT04949464NAUpdated Aug 19, 2026
Sponsor: AIDS Malignancy Consortium
HIV Infection · Tobacco-Related Carcinoma
United States
Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene AbnormalitiesRecruiting
NCT04683250Phase 1, Phase 2Updated Aug 19, 2026
Sponsor: Taiho Pharmaceutical Co., Ltd.
RET-altered Non Small Cell Lung Cancer · RET-altered Solid Tumors
United States, Australia, Japan, South Korea
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed OsteosarcomaSuspended
NCT05691478Phase 2, Phase 3Updated Aug 19, 2026
Sponsor: National Cancer Institute (NCI)
High Grade Osteosarcoma · Localized Osteosarcoma · Metastatic Osteosarcoma · Secondary Osteosarcoma
United States, Australia, Canada, New Zealand
Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene AmplificationsTerminated
NCT05827614Phase 1Updated Aug 19, 2026
Sponsor: Boundless Bio, Inc.
Triple Negative Breast Cancer (TNBC) · High Grade Serous Ovarian Carcinoma · High Grade Endometrial Carcinoma · Anogenital Cancer
United States
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell HistiocytosisRecruiting
NCT05828069Phase 2Updated Aug 19, 2026
Sponsor: National Cancer Institute (NCI)
Recurrent Langerhans Cell Histiocytosis · Refractory Langerhans Cell Histiocytosis
United States, Australia, Canada
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone SurgeryRecruiting
NCT02734537Phase 2Updated Aug 19, 2026
Sponsor: ECOG-ACRIN Cancer Research Group
Head and Neck Squamous Cell Carcinoma · Hypopharyngeal Squamous Cell Carcinoma · Laryngeal Squamous Cell Carcinoma · Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant
United States
Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial ChemotherapyRecruiting
NCT06724237Phase 3Updated Aug 19, 2026
Sponsor: Eastern Cooperative Oncology Group
Anaplastic Large Cell Lymphoma, ALK-Negative · Follicular Helper T-Cell Lymphoma · Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type · Peripheral T-Cell Lymphoma, Not Otherwise Specified
United States, Mexico
Epcoritamab in Combination With R-CHOP for Patients With Aggressive Non-Hodgkin LymphomaNot Yet Recruiting
NCT07588698Phase 2Updated Aug 19, 2026
Sponsor: Carrie Ho, MD
Non-Hodgkin's B-cell Lymphoma · Lymphoma Non-Hodgkin · Diffuse Large B-Cell Lymphoma (DLBCL)
United States
Subscapularis Repair Augmentation for Total Shoulder ArthroplastyRecruiting
NCT05487677NAUpdated Aug 19, 2026
Sponsor: Stanford University
Shoulder Injuries
United States
A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)Recruiting
NCT06789445Phase 1, Phase 2Updated Aug 19, 2026
Sponsor: BlueRock Therapeutics
Primary Photoreceptor Disease · Retinitis Pigmentosa (RP) · Usher Syndrome · Inherited Retinal Disease (IRD)
United States
A Study to Learn About Flu and COVID-19 Vaccine Responses in Healthy PeopleCompleted
NCT06683352Phase 1, Phase 2Updated Aug 19, 2026
Sponsor: BioNTech SE
Influenza,Human · COVID-19
United States
Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung CancerActive Not Recruiting
NCT04092283Phase 3Updated Aug 19, 2026
Sponsor: National Cancer Institute (NCI)
Recurrent Lung Non-Small Cell Carcinoma · Stage III Lung Cancer AJCC v8 · Stage IIIA Lung Cancer AJCC v8 · Stage IIIB Lung Cancer AJCC v8
United States, Guam
Telehealth for the Self-Management of Dietary Quality of Life in Patients After Stomach Cancer SurgeryActive Not Recruiting
NCT05203627NAUpdated Aug 19, 2026
Sponsor: City of Hope Medical Center
Gastric Carcinoma · Gastroesophageal Junction Adenocarcinoma
United States
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for VeteransRecruiting
NCT06162741NAUpdated Aug 19, 2026
Sponsor: VA Office of Research and Development
Post Traumatic Stress Disorder (PTSD) · Depression · Anxiety
United States
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular AtrophyRecruiting
NCT07287982Phase 2Updated Aug 19, 2026
Sponsor: argenx
Spinal Muscular Atrophy (SMA)
United States, United Kingdom
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and ProteinuriaActive Not Recruiting
NCT05196035Phase 3Updated Aug 19, 2026
Sponsor: Bayer
Chronic Kidney Disease · Proteinuria
United States, Argentina, Australia, Austria, Belgium +27 more
ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol StudyActive Not Recruiting
NCT06565065NAUpdated Aug 19, 2026
Sponsor: Western University of Health Sciences
Healthy
United States
Eat, Move, Live Intervention in Reducing Chronic Disease Risk in Medically Vulnerable CommunitiesActive Not Recruiting
NCT02513407NAUpdated Aug 19, 2026
Sponsor: City of Hope Medical Center
Healthy Subject
United States
Pimavanserin vs. Quetiapine for Treatment of Parkinson's PsychosisRecruiting
NCT04373317Phase 4Updated Aug 19, 2026
Sponsor: VA Office of Research and Development
Parkinson's Disease Psychosis
United States
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic LeukaemiaRecruiting
NCT06137118Phase 1, Phase 2Updated Aug 19, 2026
Sponsor: AstraZeneca
B-cell Acute Lymphoblastic Leukemia (B-ALL)
United States, Australia, Brazil, Canada, China +8 more
A Trial to Evaluate the Effect of CD388/MK1406 on the Immunogenicity of Fluzone® HD Vaccine (CD388.SQ.1.08/MK-1406-007)Active Not Recruiting
NCT07300085Phase 1Updated Aug 19, 2026
Sponsor: Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Healthy Participants
United States
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)Recruiting
NCT05489705N/AUpdated Aug 19, 2026
Sponsor: Bristol-Myers Squibb
Obstructive Hypertrophic Cardiomyopathy
United States, Austria, Czechia, France, Germany +4 more

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