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Results for “Roche”

Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation TrialNot Yet Recruiting
NCT07759700NAUpdated Aug 12, 2026
Sponsor: Poitiers University Hospital
Permanent Atrial Fibrillation · Preserved Ejection Fraction
Zoledronate Early to Hip Fracture Patients - Safe and Effective?Completed
NCT05025293Phase 4Updated Aug 12, 2026
Sponsor: Lene Bergendal Solberg
Hip Fractures · Osteoporosis
Norway
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast CancerRecruiting
NCT03424005Phase 1, Phase 2Updated Aug 12, 2026
Sponsor: Hoffmann-La Roche
Metastatic Breast Cancer
United States, Australia, France, Germany, Israel +4 more
A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)Active Not Recruiting
NCT06402838Phase 2Updated Aug 12, 2026
Sponsor: Hoffmann-La Roche
Alzheimer's Disease
Chile, Denmark, France, Germany, Italy +4 more
Obinutuzumab in Primary MNCompleted
NCT05050214Phase 2Updated Aug 11, 2026
Sponsor: Mario Negri Institute for Pharmacological Research
Membranous Nephropathy
Italy
A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart DiseaseRecruiting
NCT07495813Phase 1Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Stable Coronary Artery Disease · Healthy Volunteers
Netherlands
PopSci CHW4CervixHealthRecruiting
NCT07336134NAUpdated Aug 11, 2026
Sponsor: Thomas Jefferson University
Cervical Cancer · Hpv · Human Papilloma Virus · HPV Infection
United States
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene TherapyRecruiting
NCT05861999Phase 4Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Muscular Atrophy, Spinal
United States, Germany, Israel, Poland, Qatar +1 more
Trial to Evaluate Efficacy and Safety of Subcutaneous Mosunetuzumab in Previously Untreated Low Tumor Burden Follicular Lymphoma .Recruiting
NCT07191249Phase 2Updated Aug 11, 2026
Sponsor: Tel-Aviv Sourasky Medical Center
Follicular Lymphoma
Israel
A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast CancerRecruiting
NCT07405801Phase 2Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Breast Cancer
United States, Argentina, Brazil, Canada, France +7 more
A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related ComorbidityActive Not Recruiting
NCT06965413Phase 2Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Obesity · Overweight · Overweight With One Weight Related Comorbidity
United States, Poland, Spain, United Kingdom
A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)Recruiting
NCT05199688Phase 3Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Neuromyelitis Optica Spectrum Disorder · NMOSD
United States, Argentina, China, France, Italy +4 more
A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical TrialActive Not Recruiting
NCT02320435Phase 3Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Solid Tumors
Brazil, China, Costa Rica, France, Germany +10 more
A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple SclerosisCompleted
NCT05232825Phase 3Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Relapsing Multiple Sclerosis · Primary Progressive Multiple Sclerosis
United States, Brazil, Czechia, Italy, New Zealand +3 more
A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)Recruiting
NCT07161258Phase 2Updated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Relapsing Multiple Sclerosis
Argentina, Brazil, Mexico, Poland, Portugal +2 more
A Study to Evaluate the Effectiveness and Safety of Inavolisib in Participants With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast CancerRecruiting
NCT07347600N/AUpdated Aug 11, 2026
Sponsor: Hoffmann-La Roche
Locally Advanced Breast Cancer · Metastatic Breast Cancer
China
Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell LymphomaActive Not Recruiting
NCT02436707Phase 2Updated Aug 11, 2026
Sponsor: Canadian Cancer Trials Group
Lymphoma
Canada
A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC)Recruiting
NCT07416552Phase 1Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Metastatic Colorectal Cancer
United States
A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell CarcinomaActive Not Recruiting
NCT05805501Phase 2Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Renal Cell Carcinoma
United States, Australia, China, France, Germany +4 more
A Gene Delivery Study to Evaluate the Safety and Expression of Delandistrogene Moxeparvovec in Participants Under the Age of Four With Duchenne Muscular Dystrophy (DMD)Active Not Recruiting
NCT06128564Phase 2Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Duchenne Muscular Dystrophy
Belgium, France, Germany, Italy, Spain +1 more
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or OverweightActive Not Recruiting
NCT07499050Phase 1Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Healthy Volunteers · Overweight or Obesity
China
A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)Terminated
NCT06961370Phase 1Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Geographic Atrophy · Age-related Macular Degeneration
United States
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast CancerRecruiting
NCT07100106Phase 1, Phase 2Updated Aug 10, 2026
Sponsor: Genentech, Inc.
Breast Cancer
United States, Australia, Brazil, Canada, China +5 more
A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic DermatitisActive Not Recruiting
NCT06863961Phase 2Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Atopic Dermatitis
United States, Brazil, Canada, France, Germany +3 more
GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's DiseaseActive Not Recruiting
NCT05686551Phase 2Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Huntington Disease
United States, Argentina, Australia, Austria, Canada +10 more

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