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Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR TrialRecruiting
NCT04402788Phase 2, Phase 3Updated Aug 10, 2026
Sponsor: National Cancer Institute (NCI)
Extensive Stage Lung Small Cell Carcinoma
United States
A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA)Recruiting
NCT07340827Phase 3Updated Aug 10, 2026
Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Infertility
Japan
Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering From Gender DysphoriaRecruiting
NCT06351501Phase 3Updated Aug 10, 2026
Sponsor: Assistance Publique - Hôpitaux de Paris
Gender Dysphoria
France
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)Recruiting
NCT07405164Phase 3Updated Aug 10, 2026
Sponsor: Merck Sharp & Dohme LLC
Von Hippel-Lindau Disease · Malignant Neoplasms
United States, Australia, Belgium, Brazil, Chile +16 more
Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of CareRecruiting
NCT07195591Phase 3Updated Aug 10, 2026
Sponsor: GT Medical Technologies, Inc.
Glioblastoma
United States
OLE Study With Filgotinib in JIARecruiting
NCT07553182Phase 3Updated Aug 10, 2026
Sponsor: Alfasigma S.p.A.
Juvenile Idiopathic Arthritis (JIA)
France, Germany, United Kingdom
Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and AdolescentsRecruiting
NCT06745557Phase 3Updated Aug 10, 2026
Sponsor: CUTISS AG
Burns
Belgium, France, Germany, Italy, Netherlands +4 more
A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's DiseaseRecruiting
NCT07298421Phase 3Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Moderately to Severely Active Crohns Disease
United States, Australia, Brazil, Mexico, Taiwan +2 more
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)Recruiting
NCT07654361Phase 3Updated Aug 10, 2026
Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Obesity · Overweight · Chronic Weight Management
United States
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)Recruiting
NCT07592689Phase 3Updated Aug 10, 2026
Sponsor: Definium Therapeutics US, Inc.
Major Depressive Disorder
United States
Phase Ⅲ Trial of Group ACYW135 Meningococcal Conjugate Vaccine in Children Aged 12-23 MonthsRecruiting
NCT07505836Phase 3Updated Aug 10, 2026
Sponsor: Sinovac Biotech Co., Ltd
Epidemic Meningitis · Meningococcal Vaccines
China
A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast CancerRecruiting
NCT07647328Phase 3Updated Aug 10, 2026
Sponsor: AstraZeneca
ER-Positive HER2-Negative Breast Cancer
United States, France, Germany, Italy, Poland +4 more
A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular LymphomaRecruiting
NCT06091254Phase 3Updated Aug 10, 2026
Sponsor: Regeneron Pharmaceuticals
Follicular Lymphoma (FL)
United States, Australia, Austria, Belgium, Brazil +14 more
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)Recruiting
NCT07266831Phase 2, Phase 3Updated Aug 10, 2026
Sponsor: Merck Sharp & Dohme LLC
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
United States, Argentina, Canada, Chile, France +4 more
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)Recruiting
NCT06943872Phase 3Updated Aug 10, 2026
Sponsor: BeOne Medicines
Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma
United States, Argentina, Australia, Austria, Belgium +16 more
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 DiabetesRecruiting
NCT07088068Phase 3Updated Aug 10, 2026
Sponsor: Sanofi
Type 1 Diabetes Mellitus
United States, Argentina, Australia, Belgium, Brazil +12 more
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction CancerRecruiting
NCT06731478Phase 3Updated Aug 10, 2026
Sponsor: Daiichi Sankyo
Gastric Cancer · Gastroesophageal Junction Cancer
United States, Argentina, Australia, Austria, Belgium +21 more
A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored StudyRecruiting
NCT05862285Phase 3Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Cancer
Belgium, Canada, China, Costa Rica, France +9 more
A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand DiseaseRecruiting
NCT06998524Phase 3Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Von Willebrand Disease, Type 3
United States, Belgium, Canada, Colombia, France +9 more
Phase Ⅲ Trial of Group ACYW135 Meningococcal Conjugate Vaccine in Children Aged 3-5 MonthsRecruiting
NCT07505810Phase 3Updated Aug 10, 2026
Sponsor: Sinovac Biotech Co., Ltd
Epidemic Meningitis · Meningococcal Vaccines
China
A Study to Evaluate GFH375 Versus Docetaxel in Participants With Non-Small Cell Lung Cancer With KRAS G12D MutationRecruiting
NCT07668752Phase 3Updated Aug 10, 2026
Sponsor: Genfleet Therapeutics (Shanghai) Inc.
KRAS G12D Mutation · NSCLC (Non-small Cell Lung Cancer)
China
A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia BRecruiting
NCT05611801Phase 3Updated Aug 10, 2026
Sponsor: Pfizer
Hemophilia A · Hemophilia B
United States, Argentina, Australia, Austria, Brazil +19 more
Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)Recruiting
NCT07509151Phase 3Updated Aug 10, 2026
Sponsor: AstraZeneca
Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated IGHV
Australia, Canada, Turkey (Türkiye), United Kingdom
A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)Recruiting
NCT07541170Phase 3Updated Aug 10, 2026
Sponsor: Hoffmann-La Roche
Non-small Cell Lung Cancer
United States
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic SeizuresRecruiting
NCT05667142Phase 3Updated Aug 10, 2026
Sponsor: Xenon Pharmaceuticals Inc.
Primary Generalized Tonic-Clonic Seizures
United States, Argentina, Australia, Austria, Belgium +15 more

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