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Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney TransplantationRecruiting
NCT06830798Phase 3Updated Jun 18, 2026
Sponsor: Alexion Pharmaceuticals, Inc.
Delayed Graft Function · DGF · Kidney Transplant
United States, Argentina, Australia, Austria, Brazil +13 more
A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent SurgeryRecruiting
NCT05156983Phase 3Updated Jun 18, 2026
Sponsor: Takeda
Coagulation Disorder
United States, Argentina, Austria, Belgium, Brazil +10 more
Global Trial in APG2575 for Patients With CLL/SLLRecruiting
NCT06104566Phase 3Updated Jun 18, 2026
Sponsor: Ascentage Pharma Group Inc.
CLL/SLL
United States, Australia, Belgium, Bulgaria, Canada +14 more
Chronic Anticoagulation With a Reduced Dose Regimen of Rivaroxaban in End-stage Renal Disease PatientsRecruiting
NCT05410275Phase 3Updated Jun 18, 2026
Sponsor: University Hospital, Tours
Chronic Hemodialysis Patients
France
The ASPIRE Trial: AchilleS tendinoPathy Treated With cortIcosteRoid injEctionsRecruiting
NCT07650396Phase 3Updated Jun 18, 2026
Sponsor: Erasmus Medical Center
Achilles Tendinopathy (AT)
Netherlands
A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)Recruiting
NCT06456580Phase 3Updated Jun 18, 2026
Sponsor: Vor Biopharma
Generalized Myasthenia Gravis
United States, Argentina, Australia, Belgium, Brazil +9 more
A Study to Evaluate Safety and Effectiveness of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Improvement of Mid-Face VolumeRecruiting
NCT06734351Phase 3Updated Jun 18, 2026
Sponsor: AbbVie
Mid Face Volume Deficit
United States
Radiation Therapy With RapidPlan Knowledge-based Planning vs Human-Driven Planning for Treatment of Prostate CancerRecruiting
NCT06625034Phase 3Updated Jun 18, 2026
Sponsor: Mayo Clinic
Prostate Carcinoma
United States
Nicorandil as Anti-inflammatory in Rheumatoid ArthritisRecruiting
NCT07516769Phase 3Updated Jun 18, 2026
Sponsor: Tanta University
Rhumatoid Arthisis
Egypt
AZD0486 1L Therapy for Elderly or Unfit Participants With LBCLRecruiting
NCT07215585Phase 3Updated Jun 18, 2026
Sponsor: AstraZeneca
Large B-cell Lymphoma
Australia, Belgium, Brazil, Canada, China +6 more
Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid SurgeryRecruiting
NCT07200180Phase 3Updated Jun 18, 2026
Sponsor: Negovsky Reanimatology Research Institute
Carotid Artery Disease · Carotid Artery Stenoses
Russia
Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial HaemorrhageRecruiting
NCT06322953Phase 3Updated Jun 18, 2026
Sponsor: Walton Centre NHS Foundation Trust
Traumatic Intracranial Haemorrhage
United Kingdom
Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune ThrombocytopeniaRecruiting
NCT07657793Phase 2, Phase 3Updated Jun 18, 2026
Sponsor: Chinese SLE Treatment And Research Group
Systemic Lupus Erythematosus · Immune Thrombocytopenia
China
Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDiesRecruiting
NCT05385432Phase 3Updated Jun 18, 2026
Sponsor: University Hospital, Tours
Renal Transplant Rejection · Induction Therapy
France
Safety and Serum Virus Neutralizing Antibody Responses of VYD2311, a COVID-19 Vaccine, and Coadministered VYD2311 With a COVID-19 VaccineRecruiting
NCT07655180Phase 3Updated Jun 17, 2026
Sponsor: Invivyd, Inc.
COVID-19
United States
Phase III Randomized International Open Label Clinical Trial of Treatment Intensification With Docetaxel Plus Apalutamide in Patients With Metastatic Hormone-sensitive Prostate Cancer Who Did Not Achieve a Deep PSA Response After Initial Treatment With Apalutamide: REINFORCE Trial.Recruiting
NCT07333066Phase 3Updated Jun 17, 2026
Sponsor: Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD
Metastatic Hormone-sensitive Prostate Cancer
France, Germany, Italy, Portugal, Spain
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With thRecruiting
NCT07655115Phase 3Updated Jun 17, 2026
Sponsor: Hospital General Universitario Gregorio Marañon
Autism Spectrum Disorders
France, Spain
Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruiting
NCT03414502Phase 3Updated Jun 17, 2026
Sponsor: University of Nebraska
Rheumatoid Arthritis
United States
Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung CancerRecruiting
NCT07473128Phase 3Updated Jun 17, 2026
Sponsor: Pharmacosmos A/S
Limited Stage Small Cell Lung Cancer
United States
Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE)Recruiting
NCT07219238Phase 2, Phase 3Updated Jun 17, 2026
Sponsor: GE Healthcare
Colorectal Cancer · Gastric Cancers · Ovarian Cancers · Pancreatic Ductal Adenocarcinoma
United States, Sweden
A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's AtaxiaRecruiting
NCT06953583Phase 3Updated Jun 16, 2026
Sponsor: Biogen
Friedreich Ataxia
United States, Australia, Austria, Brazil, Canada +11 more
A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough - China ExtensionRecruiting
NCT07650084Phase 3Updated Jun 16, 2026
Sponsor: GlaxoSmithKline
Refractory Chronic Cough
China
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric CancerRecruiting
NCT06764875Phase 3Updated Jun 16, 2026
Sponsor: AstraZeneca
HER2-positive Gastric Cancer · Gastroesophageal Junction Adenocarcinoma
United States, Argentina, Australia, Austria, Belgium +23 more
Bumetanide vs. Furosemide in CirrhosisRecruiting
NCT06941415Phase 3Updated Jun 16, 2026
Sponsor: Stacy Johnson
Cirrhosis
United States
Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in AdultsRecruiting
NCT07626437Phase 3Updated Jun 16, 2026
Sponsor: Brainfarma Industria Química e Farmacêutica S/A
Common Cold/Flu · Nasal Congestion · Nasal Obstruction
Brazil

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